Results 71 to 80 of about 105,256 (302)

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Safeguarding vitality and cognition: The role of sarcopenia in intrinsic capacity decline among octogenarians from multiple cohorts

The Journal of Nutrition, Health and Aging
Background: Sarcopenia and intrinsic capacity (IC) declines pose significant challenges to healthy aging, particularly in the rapidly growing octogenarian population.
Pi-Shan Hsu, Wei-Ju Lee, Li-Ning Peng, Wan-Hsuan Lu, Lin-Chieh Meng, Fei-Yuan Hsiao, Liang-Kung Chen   +6 more
doaj   +1 more source

Prevalence and associated factors of possible sarcopenia and sarcopenia: findings from a Chinese community-dwelling old adults cross-sectional study

BMC Geriatrics, 2022
Purpose To describe the prevalence and analyse the associated factors of possible sarcopenia and sarcopenia among community-dwelling old adults in China, in order to provide effective strategies for early prevention and treatment of sarcopenia.
Jiazhi Wang, Changge Liu, Lin Zhang, Ning Liu, Lei Wang, Jingqiong Wu, Yizhao Wang, Huimin Hao, Longjun Cao, Shilei Yuan, Liping Huang   +10 more
doaj   +1 more source

Stroke and Sarcopenia

Current Physical Medicine and Rehabilitation Reports, 2020
to evaluate recent scientific research studies related to the changes in skeletal muscle after stroke and the presence of sarcopenia in stroke survivors to establish its incidence and effects on function.Recently published findings on stroke-related sarcopenia are limited.
Manuel F, Mas, Javier, González, Walter R, Frontera   +2 more
openaire   +3 more sources

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Longitudinal changes in sarcopenia was associated with survival among cirrhotic patients

Frontiers in Nutrition
BackgroundSarcopenia is common in patients with liver cirrhosis and is an independent predictor of multiple clinical outcomes. Most studies to date have used a static assessment of sarcopenia.
Minjie Jiang, Minjie Jiang, Xin Hua, Muchen Wu, Jing Wu, Xiaotong Xu, Juan Li, Qinghua Meng   +7 more
doaj   +1 more source

Enhancing Elderly Health Through Physical Activities: Insights From a Global Bibliometric Review, 1900–2023

AGING MEDICINE, EarlyView.
Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang, Bo Xie, Can Liu, Yifan Song   +3 more
wiley   +1 more source

Testosterone and Sarcopenia

The World Journal of Men's Health, 2018
Aging affects metabolism, leading to physiological and functional impairments, and is also related to changes in body composition, including reduced skeletal muscle mass and increased body fat. These changes are correlated with the pathophysiology of sarcopenia, which is defined as age-related loss of skeletal muscle mass and strength. Low testosterone
Myung Jun Shin, Yun Kyung Jeon, In Joo Kim   +2 more
openaire   +3 more sources

Chronotype and Peripheral Clock Genes: Association With Frailty and Insomnia in Mexican Older Adults

AGING MEDICINE, EarlyView.
Chronotype, insomnia, frailty, and peripheral clock gene expression were evaluated in community‐dwelling older adults. Extreme morning chronotype was associated with lower odds of insomnia, whereas women showed higher odds of insomnia. Pre‐frail and frail participants exhibited lower peripheral clock gene expression patterns than robust individuals ...
Citlally E. Ortiz‐Vázquez, Paola Garcia‐delaTorre, Sergio Sánchez‐García, Lorena Aguilar‐Arnal, Lucía Mendoza‐Viveros   +4 more
wiley   +1 more source