Results 1 to 10 of about 102 (69)

Sargable Science

, 2020
Some queries can be optimized; others can’t. This is due to the structure of the query itself, which in turn is due to the structure of the underlying data. “Sargable” is database-speak for <em> Search ARGument ABLE </em> . ¹ A query is sargable if it <em> can </em> be optimized, e.g.
Donny Winston
openaire   +2 more sources

CCR4‐NOT subunit CCF‐1/CNOT7 promotes transcriptional activation to multiple stress responses in Caenorhabditis elegans

Aging Cell, Volume 22, Issue 4, April 2023., 2023
This study reveals a new role for the CCR4‐NOT complex in transcriptome regulation in response to environmental stress using the C. elegans model. CCF‐1/CNOT7 encoding the deadenylase subunit of the complex is required for activation of xenobiotic detoxification genes in response to stress, which in turn is critical for enhancing whole‐organism stress ...
Hadi Tabarraei, Brandon M. Waddell, Kelly Raymond, Sydney M. Murray, Ying Wang, Keith P. Choe, Cheng‐Wei Wu   +6 more
wiley   +1 more source

Core social motives explain responses to collective action issues

Social and Personality Psychology Compass, Volume 17, Issue 3, March 2023., 2023
Abstract Managing collective action issues such as pandemics and climate change requires major social and behavioral change. Dominant approaches to addressing these issues center around information provision and financial incentives to shift behavior, yet, these approaches are rarely effective without integrating insights from psychological research on
Nathaniel Geiger, Cameron Brick
wiley   +1 more source

The E262K mutation in Lamin A links nuclear proteostasis imbalance to laminopathy‐associated premature aging

Aging Cell, Volume 21, Issue 11, November 2022., 2022
Model of mutant LMNA‐mediated induction of nuclear proteotoxicity and DNA damage and its impact on the onset of laminopathy‐associated progeria. LMNAE262K is increasingly aggregated in the nucleus due to its intrinsic instability coupled with structural unfolding.
Debasish Kumar Ghosh, Shruti Pande, Jeevan Kumar, Dhanya Yesodharan, Sheela Nampoothiri, Periyasamy Radhakrishnan, Chilakala Gangi Reddy, Akash Ranjan, Katta M. Girisha   +8 more
wiley   +1 more source

WINNETOU, WHITE INNOCENCE, AND SETTLER TIME

German Life and Letters, Volume 75, Issue 4, Page 574-597, October 2022., 2022
Abstract Proclaiming ‘every generation has its Winnetou’, German network RTL ushered in the return of Winnetou to German television in 2016 with a big‐budget film trilogy, Winnetou – Der Mythos Lebt. This article analyses the Winnetou film trilogy in dialogue with Karl May's original 1893 novels and the 1960s West German westerns using the concepts of ...
Maureen O. Gallagher
wiley   +1 more source

Karl Lueger and the Reichspost: Construction of a Cult of Personality

Australian Journal of Politics &History, Volume 68, Issue 3, Page 337-358, September 2022., 2022
This article contributes to the body of research on fin‐de‐siècle Viennese and Austrian history, as well as the history of ideas and press history. It expands on the scholarship by focusing on one newspaper — the Catholic‐conservative Reichspost (affiliated with the Christian Social Party) — to analyse how it perpetuated the cult of personality ...
Chris O'Neill
wiley   +1 more source

Selection of Formal Baseline Correction Methods in Thermal Analysis

Chemical Engineering &Technology, Volume 45, Issue 2, Page 238-248, February 2022., 2022
Recommendations for formal baseline correction methods for thermal analysis data are given. When lacking physical or experimental justification, only linear baseline correction methods should be used, i.e., linear with time, linear with temperature, and linear with extent of reaction. The absence of baseline correction should also be considered.
Rebecca L. Gibson, Mark J. H. Simmons, E. Hugh Stitt, Lockhart Horsburgh, Robert W. Gallen   +4 more
wiley   +1 more source

Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in rats

Glia, Volume 68, Issue 3, Page 656-669, March 2020., 2020
Main points Microglial PI3K and its downstream targets are epigenetically regulated by histone modifications and post‐translationally by sumoylation. Microglial BDNF downstream of PI3K modulates neuronal LTP and synaptic plasticity and therefore learning and memory.
Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S. Thameem Dheen   +6 more
wiley   +1 more source

Deceleration of morphological evolution in a cryptic species complex and its link to paleontological stasis

Evolution, Volume 74, Issue 1, Page 116-131, January 2020., 2020
Abstract Morphological stasis or the absence of morphological change is a well‐known phenomenon in the paleontological record, yet it is poorly integrated with neontological evidence. Recent evidence suggests that cryptic species complexes may remain morphologically identical due to morphological stasis.
José Cerca, Christian Meyer, Dave Stateczny, Dominik Siemon, Jana Wegbrod, Gunter Purschke, Dimitar Dimitrov, Torsten H. Struck   +7 more
wiley   +1 more source

Provocative Vocatives: Slurs as Expressives

Philosophical Perspectives, EarlyView.
ABSTRACT Fifty years ago, Zwicky demonstrated the slur‐neutral counterpart vocative divergence thesis (SNCVD):Slurs occur freely as vocatives. Neutral counterparts do not. In this article, I craft a novel problem for theories of slurs. The Vocatives Problem is the challenge to explain the SNCVD. I argue that there are two strong solutions.
Robin Jeshion
wiley   +1 more source