Results 161 to 170 of about 3,612 (205)
The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling [PDF]
Nature Immunology, 2006 Toll-like receptors discriminate between different pathogen-associated molecules and activate signaling cascades that lead to immune responses.
Michael Carty +2 more
exaly +4 more sources
T-cell death following immune activation is mediated by mitochondria-localized SARM
Cell Death and Differentiation, 2012 Following acute-phase infection, activated T cells are terminated to achieve immune homeostasis, failure of which results in lymphoproliferative and autoimmune diseases.
Porkodi Panneerselvam +2 more
exaly +2 more sources
Expression of sterile-α and armadillo motif containing protein (SARM) in rheumatoid arthritis monocytes correlates with TLR2-induced IL-1β and disease activity [PDF]
Rheumatology, 2021 OBJECTIVE: Cartilage and bone damage in rheumatoid arthritis (RA) are associated with elevated IL-1β. The effects of IL-1β can be reduced by biological therapies that target IL-1β or TNFα.
Ryan S Thwaites +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Detection of SARMs in doping control analysis
Molecular and Cellular Endocrinology, 2018The class of selective androgen receptor modulators (SARMs) has been the subject of intense and dedicated clinical research over the past two decades. Potential therapeutic applications of SARMs are manifold and focus particularly on the treatment of conditions manifesting in muscle loss such as general sarcopenia, cancer-associated cachexia, muscular ...
Mario, Thevis, Wilhelm, Schänzer
openaire +2 more sources
SARM: A Congestion Control Algorithm for DTN
2012 9th International Conference on Ubiquitous Intelligence and Computing and 9th International Conference on Autonomic and Trusted Computing, 2012When congestion happens at the node of DTN, the regular approach is to delete the old message of these nodes in order to make memory space for the new arrival message to remove congestion. A new method for the selection of message to delete, congestion control routing algorithm based on Simulated Annealing and regional movement (SARM) are proposed in ...
Chengjun Wang +4 more
openaire +1 more source
SARM-S4 and metabolites detection in sports drug testing: A case report
Forensic Science International, 2011 Recently, pharmaceutical industry developed a new class of therapeutics called Selective Androgen Receptor Modulator (SARM) to substitute the synthetic anabolic drugs used in medical treatments. Since the beginning of the anti-doping testing in sports in
Martial Saugy, Norbert Baumé
exaly +2 more sources
The disordering effect of SARMs on a biomembrane model
Physical Chemistry Chemical PhysicsFrom medicine to sport, selective androgen receptor modulators have represented promising applications. Still, their interactions with lipid membranes reveal crucial physicochemical effects that could be of reference in prospective medications.
Alma Jessica Díaz-Salazar +3 more
openaire +2 more sources
Advances in SARMs anti‐doping analysis
Drug Testing and AnalysisAbstractSelective androgen receptor modulators (SARMs) are performance‐enhancing drugs (PEDs) that stimulate anabolism, increase muscle mass and strength and promote recovery from exercise. The use of SARMs in sports is considered doping and is strictly prohibited by the World Anti‐Doping Agency (WADA) and the International Federation of Horseracing ...
Kristián, Slíž, Peter, Mikuš
openaire +2 more sources
SERMs and SARMs: Detection of their activities with yeast based bioassays
The Journal of Steroid Biochemistry and Molecular Biology, 2010Selective estrogen receptor modulators (SERMs) and selective androgen receptor modulators (SARMs) are compounds that activate their cognate receptor in particular target tissues without affecting other organs. Many of these compounds will find their use in therapeutic treatments.
Bovee, T.F.H. +5 more
openaire +2 more sources
A comparison of tooth-borne and bone-anchored expansion devices in SARME
Oral and Maxillofacial Surgery, 2020Major adult maxillary transverse discrepancies are usually treated with surgically assisted rapid maxillary expansion (SARME), utilizing a combination of surgical and orthodontic techniques. Unfortunately, a consensus has not been reached on topics ranging from the best surgical technique that should be performed to the ideal expander type that should ...
T R, Barone +3 more
openaire +2 more sources