Results 91 to 100 of about 18,157,587 (245)

Immune Responses in SARS-CoV-2, SARS-CoV, and MERS-CoV Infections: A Comparative Review

open access: yes, 2022
Coronavirus, discovered in the 1960s, is able to infect human hosts and causes mild to serious respiratory problems. In the last two decades, the severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-
Irani, Soussan
core   +1 more source

Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection

open access: yesAdvanced Materials, EarlyView.
The intimate interaction between negatively charged RNA molecules and conjugated polymers in organic electrochemical transistors (OECTs) in aqueous electrolytes is investigated. It demonstrates that RNA binding reduces the volumetric capacitance of the polymer channel, enabling the development of an ultrasensitive biosensing platform capable of ...
Hong Liu   +7 more
wiley   +1 more source

Codon Usage and Phenotypic Divergences of SARS-CoV-2 Genes

open access: yes, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first occurred in Wuhan (China) in December of 2019, causes a severe acute respiratory illness with a high mortality rate, and has spread around the world.
Georgakilas, Alexandros G.   +9 more
core   +1 more source

Rapid Biosensor of SARS-CoV-2 Using Specific Monoclonal Antibodies Recognizing Conserved Nucleocapsid Protein Epitopes

open access: yes, 2022
Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by symptoms such as fever, fatigue, a sore throat, diarrhea, and coughing.
Jung Kim   +8 more
core   +1 more source

Sensitive and Spatially‐Resolved Electrochemiluminescence via Micropatterning

open access: yesAdvanced Materials Interfaces, EarlyView.
The use of a simple silica nanoparticle surface coating and patterning process can transform ordinary gold electrodes into multiplexed ECL sensing electrodes. Through spatially confined droplet formation and local ECL emission, it is possible to perform multiple analyses simultaneously from individual locations as well as intensify the ECL signal by as
Yuliang Shao   +12 more
wiley   +1 more source

Mutations and Evolution of the SARS-CoV-2 Spike Protein

open access: yes, 2022
The SARS-CoV-2 spike protein mediates target recognition, cellular entry, and ultimately the viral infection that leads to various levels of COVID-19 severities. Positive evolutionary selection of mutations within the spike protein has led to the genesis
Michael C. McGee   +11 more
core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

Reporte N°23: Vigilancia de variantes de SARS-CoV-2 en la CABA, provincias de Buenos Aires, Córdoba, Entre Ríos, Neuquén y Santa Fe. Actualización del 07/06/2021 [PDF]

open access: yes, 2021
Participantes en este reporte: Nodo secuenciación HNRG: Mercedes Nabaes; Laura Valinotto; Stephanie Goya; Mónica Natale; Silvina Lusso, Sofía Alexay; Dolores Acuña; Mariana Viegas.
Gobierno de la Provincia de Córdoba. Ministerio de Salud. Laboratorio Central   +2 more
core  

Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 positivity.

open access: yes, 2022
Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 positivity.
Woottichai Khamduang (147028)   +11 more
core   +1 more source

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

open access: yesAdvanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang   +13 more
wiley   +1 more source

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