Results 201 to 210 of about 1,242,031 (332)
Surgical Volume and Short‐Term Outcomes After Advanced Hepatectomy in the Postpandemic Era: Analysis of the Japanese National Clinical Database (2018–2023)
Annals of Gastroenterological Surgery, EarlyView.This national survey using the National Clinical Database in Japan revealed a persistent decline in the number of advanced hepatectomies, even after the COVID‐19 pandemic. Despite this trend, surgical safety was effectively maintained in the postpandemic period using risk‐adjusted metrics.Yusuke Takemura, Hideki Endo, Taizo Hibi, Ryo Seishima, Masashi Takeuchi, Hiroyuki Yamamoto, Hiromichi Maeda, Akinobu Taketomi, Yoshihiro Kakeji, Yasuyuki Seto, Hideki Ueno, Masaki Mori, Ken Shirabe, Yuko Kitagawa +13 morewiley +1 more sourceDevelopment of SARS-CoV-2 as a viral vector: A novel intranasal bivalent vaccine for SARS-CoV-2 and RSV. [PDF]
Sci AdvXu J, Chamblee M, Jiang F, Kc M, Hsu CC, Thongpan I, Chen P, Zhang Y, Chiu CT, Shamseldin MM, Amer HM, Liang X, Amer AO, Boyaka PN, Cormet-Boyaka E, Peeples ME, Li J. +16 moreeuropepmc +1 more sourceTau Amyloid Corona‐Shelled Nanoparticle‐Based Drug Screening Platform for Discovering Tau Oligomer‐Degrading Drugs
Aggregate, EarlyView.Tau amyloid corona‐shelled nanoparticles (TACONs) were synthesized by incubating gold nanoparticles (AuNPs) with tau monomers that had been pre‐reacted with heparin. These TACONs represent a promising high‐throughput screening platform for identifying tau oligomer degraders as potential therapeutic agents for Alzheimer's disease.Hyo Gi Jung, Dongsung Park, Junho Bang, Yeon Ho Kim, Jae Won Jang, Yonghwan Kim, Hyunji Kim, Seungmin Lee, Wonbin Moon, Kyo Seon Hwang, Jeong Hoon Lee, Dongtak Lee, Dae Sung Yoon +12 morewiley +1 more sourceSystematic examination of T cell responses to SARS-CoV-2 versus influenza virus reveals distinct inflammatory profile
, 2020 Jaclyn C. Law, Wan Hon Koh, Patrick Budylowski, Jonah Lin, FengYun Yue, Kento T. Abe, Bhavisha Rathod, Mélanie Girard, Zhijie Li, James M. Rini, Samira Mubareka, Allison McGeer, Adrienne K. Chan, Anne‐Claude Gingras, Tania H. Watts, Mario Ostrowski +15 moreopenalex +1 more sourceIntelligent Theranostic Systems Enabled by Aggregation‐Induced Emission in Precision Medicine
Aggregate, EarlyView.Aggregation‐induced emission (AIE) luminogens are driving a new generation of intelligent theranostic systems that integrate high‐fidelity imaging and multifunctional therapy. This review highlights how AIEgens, through restriction of intramolecular motion (RIM), enable deep‐tissue NIR‐II imaging, ultrasensitive biosensing, CRISPR‐assisted gene ...Qinqin Huang, Yanyu Chen, Shile Wang, Kan Liu, Xing‐Zhong Zhao, Xiaobo Mao, Ben Zhong Tang, Lang Rao +7 morewiley +1 more sourceAntibody responses to SARS-CoV-2 in patients with COVID-19
Nature Network Boston, 2020 Quan-xin Long, Bai-Zhong Liu, H. Deng, Gui-cheng Wu, K. Deng, Yaokai Chen, P. Liao, Jing-Fu Qiu, Yong Lin, X. Cai, Deqiang Wang, Yuan Hu, Ji-hua Ren, N. Tang, Yin-yin Xu, Li-hua Yu, Z. Mo, Fang Gong, Xiao-li Zhang, Wen-guang Tian, Li Hu, Xian-xiang Zhang, Jiang-lin Xiang, Hong-xin Du, Hua-wen Liu, Chunhui Lang, Xiao-he Luo, Shao-bo Wu, X. Cui, Zheng Zhou, Manxiang Zhu, Jing Wang, Cheng-jun Xue, Xiao-feng Li, Li Wang, Zhi-jie Li, Kun Wang, Changchun Niu, Qing-jun Yang, Xiao-jun Tang, Yong Zhang, Xia-mao Liu, Jin-jing Li, De-chun Zhang, Fan Zhang, Ping Liu, Jun Yuan, Qin Li, Jie-Li Hu, Juan Chen, A. Huang +50 moresemanticscholar +1 more sourceThe Wood equation allows consistent fitting of individual antibody responses profiles in Zika virus or SARS-CoV-2 infected patients
, 2020 Jessica Denis, Annabelle Garnier, Damien Claverie, Franck de Laval, Sarah Attoumani, Bernard Tenebray, Guillaume André Durand, Bruno Coutard, Isabelle Leparc-Goffart, Jean‐Nicolas Tournier, Sébastien Briolant, Cyril Badaut +11 moreopenalex +1 more sourceCharacterization of Breakthrough Hemolysis in Patients With Paroxysmal Nocturnal Hemoglobinuria: An International Multicenter Experience
American Journal of Hematology, EarlyView.ABSTRACT
Breakthrough hemolysis (BTH) is defined as a hemolytic exacerbation in a patient with paroxysmal nocturnal hemoglobinuria (PNH) treated with complement inhibitors (CIs). In the current era of several terminal and proximal inhibitors, there are no guidelines for defining BTH and its severity, and clinical management is not standardized.Bruno Fattizzo, Giacinto Luca Pedone, Elisabetta Metafuni, Eloise Beggiato, Valentina Giai, Esther Natalie Oliva, Antony Ricchiuti, Marta Bortolotti, Simona Raso, Daniela Carlino, Mara Memoli, Sofia Vecchi, Jennifer Vidler, Sukanya Gogoi, Shreya Goel, Anna Corby, Roochi Trikha, Sneha Balakrishnan, Francesco Passamonti, Anna Paola Iori, Simona Sica, Shreyans Gandhi, Wilma Barcellini, Austin Kulasekararaj +23 morewiley +1 more source