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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans [PDF]
, 2020 Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans. Using diverse assays for antibodies recognizing SARS-CoV-2 proteins, we detect preexisting humoral immunity.
Agua-Doce, A +46 more
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International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic [PDF]
, 2022 BACKGROUND: Data from the early pandemic revealed that 0.62% of children hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had an acute arterial ischemic stroke (AIS).
Agner, Shannon C +19 more
core +2 more sources
Molecular Crowding Modulates SARS‐CoV‐2 Aptamer Affinity
Small Structures, 2023 SARS‐CoV‐2 aptamer is a favorable candidate for the recognition and detection of SARS‐CoV‐2, owing to its small size and easy synthesis. However, the issue of compromised binding affinities in real samples and targeting mutant SARS‐CoV‐2 hinder wide ...
Ting Song +6 more
doaj +1 more source
Aptamer‐based strategies against SARS‐CoV‐2 viruses
BMEMat, 2023 The COVID‐19 pandemic, caused by SARS‐CoV‐2, has seriously threatened human life and security in recent years and has had a serious impact on economic development. A range of strategies, including antibodies, small‐molecule agents and vaccines, have been
Yihao Huang +7 more
doaj +1 more source
SARS-CoV-2 aberrantly elevates mitochondrial bioenergetics to induce robust virus propagation [PDF]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a 'highly transmissible respiratory pathogen, leading to severe multi-organ damage. However, knowledge regarding SARS-CoV-2-induced cellular alterations is limited.
Jun, Sangmi +12 more
core +1 more source
In-Depth Analysis of SARS-CoV-2-Specific T Cells Reveals Diverse Differentiation Hierarchies in Vaccinated Individuals [PDF]
, 2022 SARS-CoV-2 vaccines pose as the most effective approach for mitigating the COVID-19 pandemic. High-degree efficacy of SARS-CoV-2 vaccines in clinical trials indicates that vaccination invariably induces an adaptive immune response. However, the emergence
Akdogan, Mehmet Emin +9 more
core +2 more sources
Clinical & Translational Immunology, 2021 Objectives The emergence of a SARS‐CoV‐2 variant with a point mutation in the spike (S) protein, D614G, has taken precedence over the original Wuhan isolate by May 2020.
Cheryl Yi‐Pin Lee +24 more
doaj +1 more source
Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study [PDF]
, 2021 Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective
Alessandro Frati +53 more
core +1 more source
Thoracic Cancer, 2021 Several studies have highlighted that cancer patients tend to be more susceptible to develop severe infection and to die from COVID‐19. Certain medical conditions such as immunosuppression, presence of comorbidities, and underlying pulmonary damage are ...
Ana Emília Goulart Lemos +3 more
doaj +1 more source
Inhibition of SARS‐CoV‐2‐mediated thromboinflammation by CLEC2.Fc
EMBO Molecular Medicine, 2023 Thromboinflammation is the major cause of morbidity and mortality in COVID‐19 patients, and post‐mortem examination demonstrates the presence of platelet‐rich thrombi and microangiopathy in visceral organs.
Pei‐Shan Sung +3 more
doaj +1 more source