Results 1 to 10 of about 1,218,453 (287)

SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal [PDF]

, 2022
© The Author(s) 2022.BACKGROUND: Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration with more than 50 laboratories distributed ...
Portuguese network for SARS-CoV-2 genomics (Consortium)
core   +1 more source

Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2 [PDF]

, 2021
Introduction We performed a multicentre evaluation of the Elecsys® Anti-SARS-CoV-2 immunoassay (Roche Diagnostics), an assay utilising a recombinant protein representing the nucleocapsid (N) antigen, for the in vitro qualitative detection of ...
Findeisen, Peter, Kolja Hegel, Johannes, Laimighofer, Michael, Langen, Florina, Majchrzak, Mario, Mühlbacher, Annelies, Niederhauser, Christoph, Rank, Christopher M., Riester, Elena, Schönfeld, Kathrin, Tinguely, Caroline   +10 more
core   +1 more source

AmpliCoV: Rapid Whole-Genome Sequencing Using Multiplex PCR Amplification and Real-Time Oxford Nanopore MinION Sequencing Enables Rapid Variant Identification of SARS-CoV-2

Frontiers in Microbiology, 2021
Since the emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) in December 2019, the scientific community has been sharing data on epidemiology, diagnostic methods, and whole-genomic sequences almost in real time. The latter have
Annika Brinkmann, Sophie-Luisa Ulm, Steven Uddin, Sophie Förster, Dominique Seifert, Rainer Oehme, Merle Corty, Lars Schaade, Janine Michel, Andreas Nitsche   +9 more
doaj   +1 more source

SARS-CoV-2 in silico binding affinity to human leukocyte antigen (HLA) Class II molecules predicts vaccine effectiveness across variants of concern (VOC)

Scientific Reports, 2022
There is widespread concern about the clinical effectiveness of current vaccines in preventing Covid-19 caused by SARS-CoV-2 Variants of Concern (Williams in Lancet Respir Med 29:333–335, 2021; Hayawi in Vaccines 9:1305, 2021), including those identified
Spyros A. Charonis, Lisa M. James, Apostolos P. Georgopoulos   +2 more
doaj   +1 more source

Evaluation of a commercial ELISA as alternative to plaque reduction neutralization test to detect neutralizing antibodies against SARS-CoV-2

Scientific Reports, 2022
High-throughput detection of neutralizing antibodies against SARS-CoV-2 presents a valuable tool for vaccine trials or investigations of population immunity.
Natalie Hofmann, Marica Grossegesse, Markus Neumann, Lars Schaade, Andreas Nitsche   +4 more
doaj   +1 more source

Effect of SARS-CoV-2 infection in pregnancy on CD147, ACE2 and HLA-G expression [PDF]

, 2023
Introduction: Recent studies reported a differential expression of both ACE2 and CD147 in pregnant women associated to SARS-CoV-2 placental infection. The aim of this study is to further investigate the placental SARS-CoV-2 infection and the potential ...
Angelina Passaro, Chiara Marina Semprini, Daria Bortolotti, Erica Santi, Gennaro Scutiero, Giovanna Schiuma, Ines Zidi, Juana Maria Sanz, Mercedes Fernandez, Pantaleo Greco, Roberta Gafa', Roberta Rizzo, Sabrina Rizz, Silvia Beltrami   +13 more
core   +1 more source

Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal [PDF]

, 2020
Funding This study is co-funded by Fundação para a Ciência e a Tecnologia and Agência de Investigação Clínica e Inovação Biomédica [grant number 234_596874175] on behalf of the Research 4 COVID-19 call. This work is also a result of the GenomePT project [
Portuguese network for SARS-CoV-2 genomics
core   +1 more source

Risk factors for nosocomial SARS-CoV-2 infections in patients: results from a retrospective matched case–control study in a tertiary care university center [PDF]

, 2022
Background: Factors contributing to the spread of SARS-CoV-2 outside the acute care hospital setting have been described in detail. However, data concerning risk factors for nosocomial SARS-CoV-2 infections in hospitalized patients remain scarce.
Aghdassi, Seven Johannes Sam, Behnke, Michael, Brodzinski, Annika, Fucini, Giovanni-Battista, Gastmeier, Petra, Geffers, Christine, Hansen, Sonja, Kohlmorgen, Britta, Peña Diaz, Luis Alberto, Piening, Brar, Schlosser, Beate, Schneider, Sandra, Schwab, Frank, Weikert, Beate, Wiese-Posselt, Miriam, Wolff, Sebastian   +15 more
core   +1 more source

Longitudinal SARS-CoV-2 seroepidemiological investigation among healthcare workers at a tertiary care hospital in Germany

BMC Infectious Diseases, 2022
Background SARS-CoV-2 cases in Germany increased in early March 2020. By April 2020, cases among health care workers (HCW) were detected across departments at a tertiary care hospital in Berlin, prompting a longitudinal investigation to assess HCW SARS ...
Sara Tomczyk, Alexander Hönning, Julia Hermes, Marica Grossegesse, Natalie Hofmann, Janine Michel, Markus Neumann, Andreas Nitsche, Berthold Hoppe, Tim Eckmanns, Hajo Schmidt-Traub, Kristina Zappel   +11 more
doaj   +1 more source

Contribution of syndecans to the cellular entry of SARS-CoV-2 [PDF]

, 2021
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel emerging pathogen causing an unprecedented pandemic in 21st century medicine.
Hudák Anett, Letoha Annamária, Letoha Tamás, Szilák László   +3 more
core   +1 more source