Results 121 to 130 of about 1,252,032 (378)

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans [PDF]

, 2020
Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans. Using diverse assays for antibodies recognizing SARS-CoV-2 proteins, we detect preexisting humoral immunity.
Agua-Doce, A, Beale, R, Benton, DJ, Bolland, W, Cherepanov, P, Ciurtin, C, Cornish, GH, Earl, C, Faulkner, N, Gamblin, SJ, Gandhi, S, Harvey, R, Heaney, J, Hobson, P, Houlihan, CF, Hussain, S, Jebson, BR, Joshi, D, Kassiotis, G, Kjaer, S, Marshall, LR, McCauley, J, McCoy, LE, Moore, C, Nastouli, E, Ng, KW, O'Reilly, N, Paraskevopoulou, S, Peckham, H, Radziszewska, A, Rickman, H, Riddell, A, Rosa, A, Rosser, EC, Roustan, C, Sanchez, E, Shin, GY, Spyer, MJ, Stockinger, B, Swanton, C, Thompson, R, Thomson, K, Ulferts, R, Walker, PA, Wedderburn, LR, Wilkinson, M, Wrobel, AG   +46 more
core  

Fluorinated Graphene‐Coated N95 Respirators for Enhanced Protection against Viral Accumulation and Transmission

Advanced Engineering Materials, EarlyView.
We develop a one‐step spray coating approach to coat the fluorinated graphene (FG) nanosheet onto the N95 respirators. The spray‐coated superhydrophobic N95 respirators can effectively repel respiratory droplets off instantaneously and prevent SARS‐CoV‐2 virus accumulation on the surface.
Fengjie He, Jiongyu Zhang, Shengjie Zhai, Changchun Liu, Hui Zhao   +4 more
wiley   +1 more source

Follow-up SARS-CoV-2 serological study of a health care worker cohort following COVID-19 booster vaccination

BMC Infectious Diseases
Background Studies have shown that Omicron breakthrough infections can occur at higher SARS-CoV-2 antibody levels compared to previous variants. Estimating the magnitude of immunological protection induced from COVID-19 vaccination and previous infection
Alexander Hönning, Sara Tomczyk, Julia Hermes, Marica Grossegesse, Natalie Hofmann, Janine Michel, Markus Neumann, Andreas Nitsche, Berthold Hoppe, Tim Eckmanns, Hajo Schmidt-Traub, Kristina Zappel   +11 more
doaj   +1 more source

Genomic Sequencing and Phylogenomics of Cowpox Virus

Viruses, 2022
Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian
Diana Diaz-Cánova, Carla Mavian, Annika Brinkmann, Andreas Nitsche, Ugo Moens, Malachy Ifeanyi Okeke   +5 more
doaj   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

Viral and cellular translation during SARS‐CoV‐2 infection

FEBS Open Bio, 2022
SARS‐CoV‐2 is a betacoronavirus that emerged in China in December 2019 and which is the causative agent of the Covid‐19 pandemic. This enveloped virus contains a large positive‐sense single‐stranded RNA genome.
Gilbert Eriani, Franck Martin
doaj   +1 more source

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

Science, 2021
Unmitigated spread in Brazil Despite an extensive network of primary care availability, Brazil has suffered profoundly during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Using daily data from state health offices, Castro et
N. Faria, T. Mellan, C. Whittaker, I. Claro, D. Candido, Swapnil Mishra, M. Crispim, F. C. Sales, I. Hawryluk, J. McCrone, R. Hulswit, L. A. Franco, M. Ramundo, J. D. de Jesus, P. S. Andrade, T. Coletti, G. M. Ferreira, Camila A. M. Silva, E. Manuli, R. Pereira, P. Peixoto, M. Kraemer, N. Gaburo, C. C. Camilo, H. Hoeltgebaum, W. M. Souza, E. C. Rocha, L. M. de Souza, M. D. de Pinho, L. J. Araujo, F. Malta, A. B. de Lima, J. P. Silva, D. Zauli, A. C. Ferreira, R. Schnekenberg, D. Laydon, P. Walker, Hannah M. Schlüter, A. L. dos Santos, Maria S. Vidal, Valentina S Del Caro, R. F. F. Filho, H. M. dos Santos, R. S. Aguiar, J. Proença-Módena, B. Nelson, J. Hay, M. Monod, Xenia Miscouridou, H. Coupland, R. Sonabend, M. Vollmer, A. Gandy, C. A. Prete, V. Nascimento, M. Suchard, T. Bowden, Sergei L Kosakovsky Pond, Chieh-Hsi Wu, O. Ratmann, N. Ferguson, C. Dye, N. Loman, P. Lemey, A. Rambaut, N. Fraiji, M. P. S. S. Carvalho, O. Pybus, S. Flaxman, S. Bhatt, E. Sabino   +71 more
semanticscholar   +1 more source

Droplet evaporation residue indicating SARS-COV-2 survivability on surfaces

, 2020
SARS-CoV-2 survives and remains viable on surfaces for several days under different environments as reported in recent studies. However, it is unclear how the viruses survive for such a long time and why their survivability varies across different ...
He, Zilong, Hong, Jiarong, Kumar, S. Santosh, Li, Jiaqi, Shao, Siyao, Sokoloff, J. B.   +5 more
core   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

SARS-CoV-2 Infection in Children

New England Journal of Medicine, 2020
SARS-CoV-2 Infection in Children In this report, investigators in Wuhan, China, describe the spectrum of Covid-19 illness in children under the age of 16 years.
Xiaoxia Lu, Liqiong Zhang, H. Du, Jingjing Zhang, Yuan Li, Jingyu Qu, Wenxin Zhang, Youjie Wang, Shuangshuang Bao, Ying Li, Chuansha Wu, Hongxiu Liu, Di Liu, J. Shao, Xuehua Peng, Yonghong Yang, Zhi-sheng Liu, Yun Xiang, Furong Zhang, Rona M. Silva, K. Pinkerton, K. Shen, Han Xiao, Shunqing Xu, G. Wong   +24 more
semanticscholar   +1 more source