Results 121 to 130 of about 24,947,267 (297)
, 2022 Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by symptoms such as fever, fatigue, a sore throat, diarrhea, and coughing.
Jung Kim +8 more
core +1 more source
Advanced Science, EarlyView.Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem +24 more
wiley +1 more source
Global Reproductive Health, 2020 With the SARS-CoV-2 pandemic creating such a wide-reaching health crisis, it is imperative that a safe and effective vaccine be developed promptly for global availability. As such, there are several vaccine development projects currently underway aiming to meet this critical demand.
openaire +3 more sources
Advanced Science, EarlyView.USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li +10 more
wiley +1 more source
SARS-CoV-2 Cross-reactive T cells.
, 2021 (A) CD154 upregulation assay of potential cross-reactive epitopes. Top panel: DR0101 SARS- CoV-2 S961-980, middle panel: DR1501 SARS-CoV-2 S1001-1020, and bottom panel: DP0401 SARS-CoV-2 S809-828. SARS-CoV-2 peptide-specific cell lines were generated and
Uma Malhotra (847242) +7 more
core +1 more source
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Advanced Science, EarlyView.Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source
Surveillance of seasonal respiratory viruses among Chilean patients during the COVID‐19 pandemic
Health Science Reports, 2021 Luis A. Alonso‐Palomares +8 more
doaj +1 more source
SARS-CoV-2 ORF8, rather than SARS-CoV ORF8, has an unconventional secretion pattern.
, 2023 (A) Structures of SARS-CoV-2 ORF8 and its signal peptide-deleted mutant. (B, C) Full-length SARS-CoV-2 ORF8 or its signal peptide-deleted mutant was transfected into Calu-3 cells or HEK-293FT cells. The secretion of ORF8 was detected by western blotting (
Dusan Kunec (4341475) +10 more
core +1 more source
Reporte nº4 – Provincia de Córdoba –19 de agosto de 2020. Consorcio interinstitucional para la Secuenciación del genoma y estudios genómicos de SARSCOV-2 (Proyecto PAIS) [PDF]
, 2020 Fil: Consorcio Argentino de Genómica de SARS-CoV-2; Argentina.Fil: Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología Dr. José María Vanella; Argentina.Fil: Gobierno de la Provincia de Córdoba.
Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Instituto de Virología Dr. José María Vanella; Argentina +2 more
core +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
Advanced Science, EarlyView.This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source