Results 151 to 160 of about 1,048,158 (273)

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Single‐Target Pairing System (StarPair) for Large‐Scale Interrogation of Cell–Cell Interactions

Advanced Science, EarlyView.
This work presents a single‐target pairing system, StarPair, enabling cell–cell interaction studies by target combination in droplets. StarPair offers superior pairing efficiencies over 95% and operation frequencies of 105 pairs per 9.5 h for two‐target pairing, allowing large‐scale interrogation of immune cell‐cancer cell interactions and precise ...
Tianjiao Mao, Lang Nan, Miao Xu, Kehao Zeng, Yuchao Wang, Ziyu Han, Ho Cheung Shum   +6 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Bilateral subscapular hematoma following SARS‐CoV‐2 vaccination

Health Science Reports, 2023
Osamu Imataki, Makiko Uemura
doaj   +1 more source

Antibody Resistance of SARS-CoV-2 Omicron BA.1, BA.1.1, BA.2 and BA.3 Sub-lineages [PDF]

, 2022
Jingwen Ai, Xun Wang, Xinyi He, Xiaoyu Zhao, Yi Zhang, Yuchao Jiang, Minghui Li, Yuchen Cui, Yanjia Chen, Rui Qiao, Lin Li, Lulu Yang, Yi Li, Zixin Hu, Wenhong Zhang, Pengfei Wang   +15 more
openalex   +1 more source

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

Advanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye, Xiaoli Zhang, Lingfeng Qiu, Jia Ji, Jueqing Gu, Hongyu Jia, Yingfeng Lu, Jiyang Chen, Zelu Meng, Jiangshan Lian, Hangping Yao, Xun Zeng, Yida Yang   +12 more
wiley   +1 more source

Changes in buprenorphine visits in frontier and remote locations: Effects of the SARS-CoV-2 pandemic

, 2023
Lisa M. McFadden
openalex   +1 more source

SARS-CoV-2 recruits a haem metabolite to evade antibody immunity [PDF]

, 2021
Annachiara Rosa, Valerie E. Pye, Carl Graham, Luke Muir, Jeffrey Seow, Kevin W. Ng, Nicola Cook, Chloe Rees-Spear, Eleanor Parker, Mariana Silva dos Santos, Carolina Rosadas, Alberto Susana, Hefin Rhys, Andrea Nans, Laura Masino, Chloë Roustan, Evangelos Christodoulou, Rachel Ulferts, Antoni G. Wrobel, Charlotte‐Eve Short, Michael Fertleman, Rogier W. Sanders, Judith Heaney, Moira Spyer, Svend Kjær, Andrew Riddell, Michael H. Malim, Rupert Beale, James I. MacRae, Graham P. Taylor, Eleni Nastouli, Marit J. van Gils, Peter B. Rosenthal, Massimo Pizzato, Myra O. McClure, Richard S. Tedder, George Kassiotis, Laura E. McCoy, Katie J. Doores, Peter Cherepanov   +39 more
openalex   +1 more source

Mucin‐Inspired Filamentous Sulfated Copolymers Effectively Inhibit Human Respiratory Syncytial Virus (hRSV) Infectivity

Advanced Science, EarlyView.
Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej, Enyu Xie, Kai Ludwig, Robert F. Schmidt, Yannic Kerkhoff, Robert Dalgliesh, Nilanjan Paul, Michael Gradzielski, Andreas Herrmann, Christian Sieben, Rainer Haag   +10 more
wiley   +1 more source

Protocol for studying co-infection between SARS-CoV-2 and Staphylococcus aureus in vitro

, 2023
Mariya I. Goncheva, David E. Heinrichs
openalex   +1 more source