Results 221 to 230 of about 1,228,387 (374)
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun+7 more
wiley +1 more source
SARS‐CoV heptad repeat 2 is a trimer of parallel helices
Jessica Celigoy+2 more
openalex +1 more source
Potential for SARS-CoV-2 Virus Exposure During Gynaecological Procedures
Claire Shannon‐Lowe+3 more
openalex +1 more source
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan+16 more
wiley +1 more source
Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity [PDF]
SARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is a paucity of studies on SARS-CoV-2 antiviral immunity in African children.
Adriaanse, M+30 more
core
USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang+9 more
wiley +1 more source