Results 221 to 230 of about 1,228,387 (374)

Perovskite‐Graphene Heterostructure Biosensor Integrated with Biotunable Nanoplasmonic Ternary Logic Gate for Ultrasensitive Cytokine Detection

open access: yesAdvanced Science, EarlyView.
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun   +7 more
wiley   +1 more source

SARS‐CoV heptad repeat 2 is a trimer of parallel helices

open access: green, 2011
Jessica Celigoy   +2 more
openalex   +1 more source

Potential for SARS-CoV-2 Virus Exposure During Gynaecological Procedures

open access: green, 2020
Claire Shannon‐Lowe   +3 more
openalex   +1 more source

SARS-COV-2 in Argentina

open access: yesJBRA Assisted Reproduction, 2020
Stella Lancuba, A Gustavo Martínez
openaire   +3 more sources

PIM1 Attenuates Innate Immunity to Foster Coronavirus Replication through Ubiquitin Ligase β‐TrCP‐Mediated IFNAR1 Degradation

open access: yesAdvanced Science, EarlyView.
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan   +16 more
wiley   +1 more source

Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity [PDF]

open access: yes
SARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is a paucity of studies on SARS-CoV-2 antiviral immunity in African children.
Adriaanse, M   +30 more
core  

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

open access: yesAdvanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang   +9 more
wiley   +1 more source

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