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Importance In December 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) emerged in China and has spread globally, creating a pandemic. Information about the clinical characteristics of infected patients who require
G. Grasselli+20 more
semanticscholar +1 more source
SARS-CoV-2: is there neuroinvasion? [PDF]
Abstract Background SARS-CoV-2, a coronavirus (CoV), is known to cause acute respiratory distress syndrome, and a number of non-respiratory complications, particularly in older male patients with prior health conditions, such as obesity, diabetes and hypertension.
Conor McQuaid, Molly Brady, Rashid Deane
openaire +4 more sources
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral
R. Yan+5 more
semanticscholar +1 more source
Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV isolated from an 18-year-old male living in Northern Norway.
Diana Diaz-Cánova+4 more
doaj +1 more source
The proximal origin of SARS-CoV-2
SARS-CoV-2 is the seventh coronavirus known to infect humans; SARSCoV, MERS-CoV and SARS-CoV-2 can cause severe disease, whereas HKU1, NL63, OC43 and 229E are associated with mild symptoms6. Here we review what can be deduced about the origin of SARS-CoV-
K. Andersen+5 more
semanticscholar +1 more source
The design of Indonesian SARS‐CoV‐2 primers based on phylogenomic analysis of the SARS‐CoV‐2 clades
Molecular detection needs to be augmented for COVID‐19 detection in Indonesia using the PCR method with primer‐based gene analysis. This is necessary because the RNA of the SARS‐CoV‐2 virus, the causative infectious agent of the pandemic, has been ...
Tsania Taskia Nabila+3 more
doaj +1 more source
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.
This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identify possible means of non-respiratory transmission.
Wenling Wang+6 more
semanticscholar +1 more source
2019 Novel Coronavirus (COVID-19) Pandemic: Built Environment Considerations To Reduce Transmission. [PDF]
With the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in coronavirus disease 2019 (COVID-19), corporate entities, federal, state, county, and city governments, universities, school districts, places of worship,
Coil, David A+5 more
core +2 more sources
The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic.
Alexander E. Susan C. Ralph S. Raoul J. Christian Anastasia Gorbalenya Baker Baric de Groot Drosten Gulyaeva H+17 more
semanticscholar +1 more source
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
Variable memory Immune memory against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) helps to determine protection against reinfection, disease risk, and vaccine efficacy.
J. Dan+20 more
semanticscholar +1 more source