Results 21 to 30 of about 1,252,032 (378)

Multicentre Performance Evaluation of the Elecsys Anti-SARS-CoV-2 Immunoassay as an Aid in Determining Previous Exposure to SARS-CoV-2 [PDF]

, 2021
Introduction We performed a multicentre evaluation of the Elecsys® Anti-SARS-CoV-2 immunoassay (Roche Diagnostics), an assay utilising a recombinant protein representing the nucleocapsid (N) antigen, for the in vitro qualitative detection of ...
Findeisen, Peter, Kolja Hegel, Johannes, Laimighofer, Michael, Langen, Florina, Majchrzak, Mario, Mühlbacher, Annelies, Niederhauser, Christoph, Rank, Christopher M., Riester, Elena, Schönfeld, Kathrin, Tinguely, Caroline   +10 more
core   +1 more source

SARS-CoV-2: is there neuroinvasion? [PDF]

Fluids and Barriers of the CNS, 2021
Abstract Background SARS-CoV-2, a coronavirus (CoV), is known to cause acute respiratory distress syndrome, and a number of non-respiratory complications, particularly in older male patients with prior health conditions, such as obesity, diabetes and hypertension.
Conor McQuaid, Molly Brady, Rashid Deane
openaire   +4 more sources

Effect of SARS-CoV-2 infection in pregnancy on CD147, ACE2 and HLA-G expression [PDF]

, 2023
Introduction: Recent studies reported a differential expression of both ACE2 and CD147 in pregnant women associated to SARS-CoV-2 placental infection. The aim of this study is to further investigate the placental SARS-CoV-2 infection and the potential ...
Angelina Passaro, Chiara Marina Semprini, Daria Bortolotti, Erica Santi, Gennaro Scutiero, Giovanna Schiuma, Ines Zidi, Juana Maria Sanz, Mercedes Fernandez, Pantaleo Greco, Roberta Gafa', Roberta Rizzo, Sabrina Rizz, Silvia Beltrami   +13 more
core   +1 more source

The design of Indonesian SARS‐CoV‐2 primers based on phylogenomic analysis of the SARS‐CoV‐2 clades

Indonesian Journal of Biotechnology, 2022
Molecular detection needs to be augmented for COVID‐19 detection in Indonesia using the PCR method with primer‐based gene analysis. This is necessary because the RNA of the SARS‐CoV‐2 virus, the causative infectious agent of the pandemic, has been ...
Tsania Taskia Nabila, Ata Rofita Wasiati, Afif Pranaya Jati, Annisa Khumaira   +3 more
doaj   +1 more source

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.

Journal of the American Medical Association (JAMA), 2020
Importance In December 2019, a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) emerged in China and has spread globally, creating a pandemic. Information about the clinical characteristics of infected patients who require
G. Grasselli, A. Zangrillo, A. Zanella, M. Antonelli, L. Cabrini, A. Castelli, D. Cereda, A. Coluccello, G. Foti, R. Fumagalli, G. Iotti, N. Latronico, L. Lorini, S. Merler, G. Natalini, A. Piatti, M. Ranieri, A. Scandroglio, E. Storti, M. Cecconi, A. Pesenti   +20 more
semanticscholar   +1 more source

Risk factors for nosocomial SARS-CoV-2 infections in patients: results from a retrospective matched case–control study in a tertiary care university center [PDF]

, 2022
Background: Factors contributing to the spread of SARS-CoV-2 outside the acute care hospital setting have been described in detail. However, data concerning risk factors for nosocomial SARS-CoV-2 infections in hospitalized patients remain scarce.
Aghdassi, Seven Johannes Sam, Behnke, Michael, Brodzinski, Annika, Fucini, Giovanni-Battista, Gastmeier, Petra, Geffers, Christine, Hansen, Sonja, Kohlmorgen, Britta, Peña Diaz, Luis Alberto, Piening, Brar, Schlosser, Beate, Schneider, Sandra, Schwab, Frank, Weikert, Beate, Wiese-Posselt, Miriam, Wolff, Sebastian   +15 more
core   +1 more source

Commercial stocks of SARS-CoV-2 RNA may report low concentration values, leading to artificially increased apparent sensitivity of diagnostic assays [PDF]

, 2020
In response to the rapidly evolving COVID-19 pandemic, the U.S. Food and Drug Administration (FDA) has rapidly issued 49 emergency use authorizations (EUAs) for SARS-CoV-2 in vitro diagnostic test-kits. A critical metric in the performance evaluation for
Ismagilov, Rustem F., Jue, Erik
core   +1 more source

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

Nature Microbiology, 2020
The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic.
Alexander E. Susan C. Ralph S. Raoul J. Christian Anastasia Gorbalenya Baker Baric de Groot Drosten Gulyaeva H, A. Gorbalenya, S. Baker, R. Baric, R. D. de Groot, C. Drosten, Anastasia A. Gulyaeva, B. Haagmans, C. Lauber, A. M. Leontovich, B. Neuman, Dmitry Penzar, S. Perlman, L. Poon, Dmitry V. Samborskiy, I. Sidorov, I. Sola, J. Ziebuhr   +17 more
semanticscholar   +1 more source

Detection of SARS-CoV-2 in Different Types of Clinical Specimens.

Journal of the American Medical Association (JAMA), 2020
This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identify possible means of non-respiratory transmission.
Wenling Wang, Yanli Xu, R. Gao, R. Lu, Kai Han, Guizhen Wu, W. Tan   +6 more
semanticscholar   +1 more source

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

Science, 2021
UK variant transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the capacity to generate variants with major genomic changes. The UK variant B.1.1.7 (also known as VOC 202012/01) has many mutations that alter virus attachment and
N. Davies, S. Abbott, R. Barnard, C. Jarvis, A. Kucharski, J. Munday, Carl A. B. Pearson, T. Russell, D. Tully, A. Washburne, T. Wenseleers, A. Gimma, W. Waites, Kerry L. M. Wong, K. van Zandvoort, J. Silverman, K. Diaz-Ordaz, R. Keogh, R. Eggo, S. Funk, M. Jit, K. Atkins, W. Edmunds   +22 more
semanticscholar   +1 more source