Results 31 to 40 of about 1,287,062 (370)

Characteristics of SARS-CoV-2 and COVID-19

open access: yesNature Reviews Microbiology, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which ...
Ben Hu, Hua Guo, P. Zhou, Zhènglì Shí
semanticscholar   +1 more source

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England

open access: yesScience, 2021
UK variant transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the capacity to generate variants with major genomic changes. The UK variant B.1.1.7 (also known as VOC 202012/01) has many mutations that alter virus attachment and
N. Davies   +22 more
semanticscholar   +1 more source

On the origins of SARS-CoV-2 [PDF]

open access: yesNature Medicine, 2021
Stakeholders in public health must lobby policy makers to make decisions based on evidence, not political expediency, particularly when the studies that hang in the balance are critical to understanding the origins of epidemics.
openaire   +3 more sources

Diagnosis and Management of COVID-19 Disease [PDF]

open access: yes, 2020
SARS-CoV-2 is a novel coronavirus that was identified in late 2019 as the causative agent of COVID-19 (aka coronavirus disease 2019). On March 11, 2020, the World Health Organization (WHO) declared the world-wide outbreak of COVID-19 a pandemic.
Carlos, Graham   +5 more
core   +1 more source

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

open access: yesNew England Journal of Medicine, 2020
SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....
L. Zou   +15 more
semanticscholar   +1 more source

SARS-CoV-2 variants, spike mutations and immune escape

open access: yesNature Reviews Microbiology, 2021
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome are expected to be either deleterious and swiftly purged or relatively neutral, a small proportion will affect functional properties and may alter ...
William T. Harvey   +10 more
semanticscholar   +1 more source

Superantigens and SARS-CoV-2

open access: yesPathogens, 2022
It has been posited SARS-CoV-2 contains at least one unique superantigen-like motif not found in any other SARS or endemic coronaviruses. Superantigens are potent antigens that can send the immune system into overdrive. SARS-CoV-2 causes many of the biological and clinical consequences of a superantigen, and, in the context of reinfection and waning ...
Adam Hamdy, Anthony Leonardi
openaire   +3 more sources

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

open access: yesNature, 2020
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individuals
D. Gordon   +124 more
semanticscholar   +1 more source

Portable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples

open access: yesScientific Reports, 2022
Loop-mediated isothermal amplification is known for its high sensitivity, specificity and tolerance to inhibiting-substances. In this work, we developed a device for performing real-time colorimetric LAMP combining the accuracy of lab-based quantitative ...
G. Papadakis   +17 more
doaj   +1 more source

Evolutionary Dynamics and Dissemination Pattern of the SARS-CoV-2 Lineage B.1.1.33 During the Early Pandemic Phase in Brazil

open access: yesFrontiers in Microbiology, 2021
A previous study demonstrates that most of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Brazilian strains fell in three local clades that were introduced from Europe around late February 2020.
Paola Cristina Resende   +29 more
doaj   +1 more source

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