Results 31 to 40 of about 1,287,062 (370)
Characteristics of SARS-CoV-2 and COVID-19
Nature Reviews Microbiology, 2020 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named ‘coronavirus disease 2019’ (COVID-19), which ...Ben Hu, Hua Guo, P. Zhou, Zhènglì Shísemanticscholar +1 more sourceEstimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
Science, 2021 UK variant transmission Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has the capacity to generate variants with major genomic changes. The UK variant B.1.1.7 (also known as VOC 202012/01) has many mutations that alter virus attachment and N. Davies, S. Abbott, R. Barnard, C. Jarvis, A. Kucharski, J. Munday, Carl A. B. Pearson, T. Russell, D. Tully, A. Washburne, T. Wenseleers, A. Gimma, W. Waites, Kerry L. M. Wong, K. van Zandvoort, J. Silverman, K. Diaz-Ordaz, R. Keogh, R. Eggo, S. Funk, M. Jit, K. Atkins, W. Edmunds +22 moresemanticscholar +1 more sourceOn the origins of SARS-CoV-2 [PDF]
Nature Medicine, 2021 Stakeholders in public health must lobby policy makers to make decisions based on evidence, not political expediency, particularly when the studies that hang in the balance are critical to understanding the origins of epidemics.openaire +3 more sourcesDiagnosis and Management of COVID-19 Disease [PDF]
, 2020 SARS-CoV-2 is a novel coronavirus that was identified in late 2019 as the causative agent of COVID-19 (aka coronavirus disease 2019). On March 11, 2020, the World Health Organization (WHO) declared the world-wide outbreak of COVID-19 a pandemic.Carlos, Graham, Dela Cruz, Charles S., Gross, Jane E., Jamil, Shazia, Mark, Nick, Pasnick, Susan +5 morecore +1 more sourceSARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients
New England Journal of Medicine, 2020 SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....L. Zou, Feng Ruan, Mingxing Huang, L. Liang, Huitao Huang, Z. Hong, Jianxiang Yu, Min Kang, Yingchao Song, J. Xia, Qianfang Guo, T. Song, Jianfeng He, H. Yen, M. Peiris, Jie Wu +15 moresemanticscholar +1 more sourceSARS-CoV-2 variants, spike mutations and immune escape
Nature Reviews Microbiology, 2021 Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome are expected to be either deleterious and swiftly purged or relatively neutral, a small proportion will affect functional properties and may alter ...William T. Harvey, A. Carabelli, B. Jackson, Ravindra K. Gupta, E. Thomson, E. Harrison, C. Ludden, R. Reeve, A. Rambaut, S. Peacock, D. Robertson +10 moresemanticscholar +1 more sourceSuperantigens and SARS-CoV-2
Pathogens, 2022 It has been posited SARS-CoV-2 contains at least one unique superantigen-like motif not found in any other SARS or endemic coronaviruses. Superantigens are potent antigens that can send the immune system into overdrive. SARS-CoV-2 causes many of the biological and clinical consequences of a superantigen, and, in the context of reinfection and waning ...Adam Hamdy, Anthony Leonardiopenaire +3 more sourcesA SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing
Nature, 2020 A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individuals D. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, K. Obernier, K. White, Matthew J. O’Meara, V. Rezelj, Jeffrey Z. Guo, D. Swaney, Tia A. Tummino, Ruth Hüttenhain, Robyn M. Kaake, Alicia L. Richards, B. Tutuncuoglu, Helene Foussard, J. Batra, Kelsey M. Haas, Mayank Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, M. J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, F. Roesch, T. Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, S. Peng, Ying Shi, Ziyang Zhang, W. Shen, I. T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, D. Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J. P. Mathy, Tina Perica, K. B. Pilla, Sai J. Ganesan, Daniel J. Saltzberg, R. Rakesh, Xi Liu, S. Rosenthal, Lorenzo Calviello, S. Venkataramanan, José M Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, Yongfeng Liu, S. Wankowicz, M. Bohn, M. Safari, Fatima S. Ugur, C. Koh, Nastaran Sadat Savar, Q. D. Tran, Djoshkun Shengjuler, S. Fletcher, M. C. O’Neal, Yiming Cai, Jason C. J. Chang, D. Broadhurst, Saker Klippsten, P. P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu-Ozturk, Hao-Yuan Wang, R. Trenker, Janet M. Young, D. A. Cavero, J. Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, R. Stroud, A. Frankel, O. Rosenberg, K. Verba, D. Agard, M. Ott, M. Emerman, N. Jura, M. von Zastrow, E. Verdin, A. Ashworth, O. Schwartz, C. d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, D. Fujimori, T. Ideker, C. Craik, S. Floor, J. Fraser, J. Gross, A. Sali, B. Roth, D. Ruggero, J. Taunton, T. Kortemme, P. Beltrão, M. Vignuzzi, A. García-Sastre, K. Shokat, B. Shoichet, N. Krogan +124 moresemanticscholar +1 more sourcePortable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples
Scientific Reports, 2022 Loop-mediated isothermal amplification is known for its high sensitivity, specificity and tolerance to inhibiting-substances. In this work, we developed a device for performing real-time colorimetric LAMP combining the accuracy of lab-based quantitative ...G. Papadakis, A. K. Pantazis, N. Fikas, S. Chatziioannidou, V. Tsiakalou, K. Michaelidou, V. Pogka, M. Megariti, M. Vardaki, K. Giarentis, J. Heaney, E. Nastouli, T. Karamitros, A. Mentis, A. Zafiropoulos, G. Sourvinos, S. Agelaki, E. Gizeli +17 moredoaj +1 more sourceEvolutionary Dynamics and Dissemination Pattern of the SARS-CoV-2 Lineage B.1.1.33 During the Early Pandemic Phase in Brazil
Frontiers in Microbiology, 2021 A previous study demonstrates that most of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Brazilian strains fell in three local clades that were introduced from Europe around late February 2020.Paola Cristina Resende, Edson Delatorre, Tiago Gräf, Daiana Mir, Fernando Couto Motta, Luciana Reis Appolinario, Anna Carolina Dias da Paixão, Ana Carolina da Fonseca Mendonça, Maria Ogrzewalska, Braulia Caetano, Gabriel Luz Wallau, Cássia Docena, Mirleide Cordeiro dos Santos, Jessylene de Almeida Ferreira, Edivaldo Costa Sousa Junior, Sandro Patroca da Silva, Sandra Bianchini Fernandes, Lucas Alves Vianna, Larissa da Costa Souza, Jean F. G. Ferro, Vanessa B. Nardy, Cliomar A. Santos, Irina Riediger, Maria do Carmo Debur, Júlio Croda, Júlio Croda, Wanderson K. Oliveira, André Abreu, Gonzalo Bello, Marilda M. Siqueira +29 moredoaj +1 more source