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Therapeutic antibodies under development for SARS‐CoV‐2

View, 2022
The world is experiencing one of the most difficult moments in history with COVID‐19, which has rapidly developed into a worldwide pandemic with a significant health and economic burden.
Zetong Ma, MengMei Zhu, Shuyi Zhang, Kewen Qian, Chuqi Wang, Wenyan Fu, Changhai Lei, Shi Hu   +7 more
doaj   +4 more sources

Seroprevalence and placental transfer of SARS-CoV-2 antibodies in unvaccinated pregnant women [PDF]

BMC Infectious Diseases
Purpose Pregnant women are at risk of severe SARS-CoV-2 infection, potentially leading to obstetric and neonatal complications. Placental transfer of antibodies directed to SARS-CoV-2 may be protective against neonatal COVID-19, but this remains to be ...
An Vercoutere, Mbiton Joel Zina, Meltem Telis, Jean-Christophe Goffard, Michel Boulvain, Loïc de Doncker, Sara Derisbourg, Sylvie Houben, Marie-Luce Delforge, Caroline Daelemans, Dorottya Kelen   +10 more
doaj   +2 more sources

Studies of SARS virus vaccines [PDF]

, 2008
1. Intranasal vaccination using inactivated SARS coronavirus (SARS-CoV) vaccine with adjuvant can induce strong systemic (serum immunoglobulin [Ig] G) and respiratory tract local (tracheal-lung wash fluid IgA) antibody responses with neutralising ...
Chan, C, Du, LY, Guan, Y, Lin, YP, Ma, S, Sui, HY, Yuen, KY, Zhao, GY, Zheng, BJ   +8 more
core   +10 more sources

SARS CoV- 2 vaccination induces antibodies against cardiolipin

BMC Research Notes, 2022
Objective Cases of thrombosis have been reported after administration of SARS-CoV-2 vaccines, with controversial results relating to Oxford-AstraZeneca’s ChAdOx1-S.
George Krashias, Anna Pafiti, Elie Deeba, Christina Christodoulou, Marios Pantzaris, Anastasia Lambrianides   +5 more
doaj   +1 more source

Pre-existing humoral immunity to low pathogenic human coronaviruses exhibits limited cross-reactive antibodies response against SARS-CoV-2 in children

Frontiers in Immunology, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes asymptomatic or mild symptoms, even rare hospitalization in children. A major concern is whether the pre-existing antibodies induced by low pathogenic human coronaviruses (LPH ...
Nina Li, Nina Li, XueYun Li, XueYun Li, Jiani Wu, Jiani Wu, Shengze Zhang, Shengze Zhang, Lin Zhu, Lin Zhu, Qiqi Chen, Qiqi Chen, Ying Fan, Ying Fan, Zhengyu Wu, Zhengyu Wu, Sidian Xie, Sidian Xie, Qi Chen, Qi Chen, Ning Wang, Nan Wu, Chuming Luo, Chuming Luo, Yuelong Shu, Yuelong Shu, Yuelong Shu, Yuelong Shu, Huanle Luo, Huanle Luo, Huanle Luo   +30 more
doaj   +1 more source

Tear antibodies to SARS‐CoV‐2: implications for transmission

Clinical & Translational Immunology, 2021
Objectives SARS‐CoV‐2 can be transmitted by aerosols, and the ocular surface may be an important route of transmission. Little is known about protective antibody responses to SARS‐CoV‐2 in tears after infection or vaccination.
Kevin J Selva, Samantha K Davis, Ebene R Haycroft, Wen Shi Lee, Ester Lopez, Arnold Reynaldi, Miles P Davenport, Helen E Kent, Jennifer A Juno, Amy W Chung, Stephen J Kent   +10 more
doaj   +1 more source

Circulating anti-SARS-CoV-2 nucleocapsid (N)-protein antibodies and anti-SARS-CoV-2 spike (S)-protein antibodies in an African setting: herd immunity, not there yet!

BMC Research Notes, 2021
Objective Herd immunity is achieved when in a population, immune individuals are in a sufficiently large proportion. Neutralizing antibodies specific to SARS-CoV-2 that are produced following infection or vaccination are critical for controlling the ...
Amandine Mveang Nzoghe, Marielle Leboueny, Eliane Kuissi Kamgaing, Anicet Christel Maloupazoa Siawaya, Eliode Cyrien Bongho, Ofilia Mvoundza Ndjindji, Guy-Stephan Padzys, Bénédicte Ndeboko, Simon Ategbo, Joel Fleury Djoba Siawaya   +9 more
doaj   +1 more source

Association between serologically confirmed COVID-19 infection and cognitive functioning in community dwelling older adults

Frontiers in Neurology, 2023
IntroductionCOVID-19 infection can impact the central nervous system, and is often associated with cognitive decline. However, there are no studies linking serologically confirmed COVID-19 infection with objectively assessed cognitive functioning.
Sabatini Serena, Pacifico Deborah, Frei Anja, Graf Gwendolyn, Milo A. Puhan, Emiliano Albanese   +5 more
doaj   +1 more source

Development of a Method for Detection of SARS-CoV-2 Nucleocapsid Antibodies on Dried Blood Spot by DELFIA Immunoassay

Diagnostics, 2023
Antibodies against the SARS-CoV-2 nucleocapsid protein are produced by the immune system in response to SARS-CoV-2 infection, but most available vaccines developed to fight the pandemic spread target the SARS-CoV-2 spike protein.
Verena Damiani, Erika Pizzinato, Ilaria Cicalini, Gianmaria Demattia, Mirco Zucchelli, Luca Natale, Claudia Palmarini, Claudia Di Marzio, Luca Federici, Vincenzo De Laurenzi, Damiana Pieragostino   +10 more
doaj   +1 more source

Human neutralising antibodies elicited by SARS‐CoV‐2 non‐D614G variants offer cross‐protection against the SARS‐CoV‐2 D614G variant

Clinical & Translational Immunology, 2021
Objectives The emergence of a SARS‐CoV‐2 variant with a point mutation in the spike (S) protein, D614G, has taken precedence over the original Wuhan isolate by May 2020.
Cheryl Yi‐Pin Lee, Siti Naqiah Amrun, Rhonda Sin‐Ling Chee, Yun Shan Goh, Tze‐Minn Mak, Sophie Octavia, Nicholas Kim‐Wah Yeo, Zi Wei Chang, Matthew Zirui Tay, Anthony Torres‐Ruesta, Guillaume Carissimo, Chek Meng Poh, Siew‐Wai Fong, Wang Bei, Sandy Lee, Barnaby Edward Young, Seow‐Yen Tan, Yee‐Sin Leo, David C Lye, Raymond TP Lin, Sebastien Maurer‐Stroh, Bernett Lee, Cheng‐I Wang, Laurent Renia, Lisa FP Ng   +24 more
doaj   +1 more source