Results 221 to 230 of about 1,320,827 (304)

A SARS-CoV-2 spike-derived adjuvant peptide boosts IL-17/IFN-γ immunity and improves anti-PD-L1 therapy against melanoma. [PDF]

Mol Med
Chen CH, Weng TH, Kuo TW, Huang KY, Chen YC, Huang HH, Kao HJ, Yu CL, Huang CC, Weng SL, Liao KW.   +10 more
europepmc   +1 more source

Morphology-Based Feature Extraction Network for Arbitrary-Oriented SAR Vehicle Detection

Ting Chen, Xiaohong Huang
openalex   +1 more source

Calibration of channel depth and friction parameters in the LISFLOOD-FP hydraulic model using medium resolution SAR data

, 2016
Melissa Wood, Renaud Hostache, Jeffrey Neal, Thorsten Wagener, Laura Giustarini, Marco Chini, Giovanni Corato, Patrick Matgen, Paul Bates   +8 more
openalex   +1 more source

Unique Aerofoil‐Structured Microfluidics for High Throughput Lipid Nanoparticle Formulation Screening and Scale‐up

Advanced Science, EarlyView.
This study presents aerofoiled microfluidic structures optimized for efficient mixing and lipid nanoparticle (LNP) formation across broad flow rates. Based on this design, two dedicated systems are introduced: MiNANO‐form for high‐throughput formulation screening and MiNANO‐scale for continuous large‐scale production, enabling reproducible, high ...
Dongsheng Liu, Mingzhi Yu, Yuguo Zhang, Allen Mathew, Tianyu Guan, Liang Yao, Xianqing Wang, Wenxin Wang, Nan Zhang   +8 more
wiley   +1 more source

Estimating COVID-19 incidence and prevalence using lateral flow tests in England and Scotland, 2023-2024. [PDF]

Nat Commun
Fyles M, Mellor J, Paton RS, Overton CE, Phillips AM, Glaser A, Ward T.   +6 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Respiratory virus dynamics in a tropical region: Insights from Yucatán, México (2018-2024). [PDF]

Epidemiol Infect
Jiménez-Rico MA, Novelo-Pérez DF, Puch-Magaña CI, Manrique-Puch RA, Puerto-Compean ML, García-López R, Pompa-Mera EN, Núñez-Armendáriz M, Sarmiento-Silva RE, Lugo-Tavera M.   +9 more
europepmc   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

Prolonged persistence of tissue-resident memory cells in the upper airway following SARS-CoV-2 infection and vaccination. [PDF]

Clin Transl Immunology
Cha H, Won J, Kim SM, Lim S, Kim S, Jin S, Cho SD, Kim HJ.   +7 more
europepmc   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source