Results 251 to 260 of about 1,320,827 (304)

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations. [PDF]

Emerg Microbes Infect
Guo Y, Tian J, Guo P, Wang X, Shang B, She J, Yang M, Gao GF, Liu J.   +8 more
europepmc   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

COVID-19 and MPXV: Twindemic Response and Dual Infections in Individuals in a US Metro. [PDF]

Epidemiologia (Basel)
Khan A, Erickson TA, Carrillo L.
europepmc   +1 more source

Space Borne SAR Traffic Monitoring [PDF]

, 2007
Hartmut Runge, Steffen Suchandt, Alexander Kotenkov, Helko Breit, Martin Vonavka, Ulrich Balss   +5 more
openalex  

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Impact of previous SARS-CoV-2 infection on the severity of respiratory syncytial virus infection in hospitalized children. [PDF]

Sci Rep
Poniedziałek B, Rozwadowski M, Zabłocka K, Jackowska T, Rzymski P.   +4 more
europepmc   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

FGFR signaling and neddylation facilitate SARS-CoV-2 infection by modulating interferon induction and viral entry, respectively. [PDF]

iScience
Felix-Lopez A, Lopez-Orozco J, Elaish M, Fayad N, Xu Z, Woldemariam T, Hassan BB, Panigrahi R, Khan JQ, Rohamare M, Mayers I, Glover JNM, Wilson JA, Falzarano D, Kumar A, Hobman TC.   +15 more
europepmc   +1 more source