Results 21 to 30 of about 520,560 (251)

The evolution of the metazoan Toll receptor family and its expression during protostome development

open access: yesBMC Ecology and Evolution, 2021
Background Toll-like receptors (TLRs) play a crucial role in immunity and development. They contain leucine-rich repeat domains, one transmembrane domain, and one Toll/IL-1 receptor domain.
Andrea Orús-Alcalde   +3 more
doaj   +1 more source

The localization of Toll and Imd pathway and complement system components and their response to Vibrio infection in the nemertean Lineus ruber

open access: yesBMC Biology, 2023
Background Innate immunity is the first line of defense against pathogens. In animals, the Toll pathway, the Imd pathway, the complement system, and lectins are well-known mechanisms involved in innate immunity.
Andrea Orús-Alcalde   +2 more
doaj   +1 more source

The visual pigment xenopsin is widespread in protostome eyes and impacts the view on eye evolution

open access: yeseLife, 2020
Photoreceptor cells in the eyes of Bilateria are often classified into microvillar cells with rhabdomeric opsin and ciliary cells with ciliary opsin, each type having specialized molecular components and physiology.
Clemens Christoph Döring   +4 more
doaj   +1 more source

Laboratory study of Fritillaria lifecycle reveals key morphogenetic events leading to genus-specific anatomy

open access: yesFrontiers in Zoology, 2022
A fascinating variety of adult body plans can be found in the Tunicates, the closest existing relatives of vertebrates. A distinctive feature of the larvacean class of pelagic tunicates is the presence of a highly specialized surface epithelium that ...
Simon Henriet   +2 more
doaj   +1 more source

Comparative Evolution of Animal and Human Coronaviruses, their Varieties and Virulence [PDF]

open access: yesJLUMHS, 2021
Coronaviruses are a group of enveloped viruses with single-stranded and RNA genomes that cause a wide-ranging spectrum of animal and human diseases.
Shabnam Rustamani
doaj   +1 more source

The development of early pioneer neurons in the annelid Malacoceros fuliginosus

open access: yesBMC Evolutionary Biology, 2020
Background Nervous system development is an interplay of many processes: the formation of individual neurons, which depends on whole-body and local patterning processes, and the coordinated growth of neurites and synapse formation.
Suman Kumar   +3 more
doaj   +1 more source

Comparison of the cardiovascular presentations, complications and outcomes following different coronaviruses’ infection: A systematic review [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2021
Manifestations caused by coronavirus family have presented it in many ways during the previous years. The aim of this systematic review was to gather all possible cardiovascular manifestations of the coronavirus family in the literature.
Mohammad Mostafa Ansari Ramandi   +7 more
doaj   +1 more source

Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR

open access: yesBMC Genomics, 2019
Background In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic.
Gemma B. Danks   +6 more
doaj   +1 more source

Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate

open access: yesBMC Genomics, 2018
Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component of this and yet few rules governing selection are known.
Gemma B. Danks   +3 more
doaj   +1 more source

Crucial contribution of the universities to SARS-CoV-2 surveillance in Ecuador: Lessons for developing countries

open access: yesOne Health, 2021
COVID-19 pandemic has challenged public health systems worldwide, particularly affecting developing countries in Latin America like Ecuador. In this report, we exposed the fundamental role of the Ecuadorian universities to improve COVID-19 surveillance ...
Daniela Santander-Gordon   +19 more
doaj   +1 more source

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