TB and COVID-19: An Exploration of the Characteristics and Resulting Complications of Co-infection
Frontiers in Bioscience-Scholar, 2022 Tuberculosis (TB) and Coronavirus Disease-19 (COVID-19) infection are two respiratory diseases that are of particular concern epidemiologically. Tuberculosis is one of the oldest diseases recorded in the history of mankind dating back thousands of years.
Erica Luke +3 more
doaj +1 more source
Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2 [PDF]
, 2020 Background and purpose Infections with coronaviruses are not always confined to the respiratory tract and various neurological manifestations have been reported.
Boon, Paul +6 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning
BMC BiologyBackground Wnt signaling pathways play crucial roles in animal development. They establish embryonic axes, specify cell fates, and regulate tissue morphogenesis from the early embryo to organogenesis.
Bruno C. Vellutini +3 more
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Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China. [PDF]
, 2020 An in-depth annotation of the newly discovered coronavirus (2019-nCoV) genome has revealed differences between 2019-nCoV and severe acute respiratory syndrome (SARS) or SARS-like coronaviruses.
Cheng, Genhong +15 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A population of Vasa2 and Piwi1 expressing cells generates germ cells and neurons in a sea anemone
Nature CommunicationsGermline segregation, essential for protecting germ cells against mutations, occurs during early embryogenesis in vertebrates, insects and nematodes.
Paula Miramón-Puértolas +2 more
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Hox gene expression in postmetamorphic juveniles of the brachiopod Terebratalia transversa
EvoDevo, 2019 Background Hox genes encode a family of homeodomain containing transcription factors that are clustered together on chromosomes of many Bilateria.
Ludwik Gąsiorowski, Andreas Hejnol
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Sino-African Philosophy: A Re-“Constructive Engagement” [PDF]
, 2019 “Constructive-Engagement” is a meta-philosophical and meta-methodological “strategy” suggested by Chinese and comparative philosophy scholar Bo Mou for analyzing and enriching philosophical exchange.
DOTTIN, Paul A.
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Methods for estimating the case fatality ratio for a novel, emerging infectious disease. [PDF]
, 2005 During the course of an epidemic of a potentially fatal disease, it is important that the case fatality ratio be well estimated. The authors propose a novel method for doing so based on the Kaplan-Meier survival procedure, jointly considering two ...
Anderson, RM +10 more
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