Results 21 to 30 of about 1,101,190 (284)
Commercial stocks of SARS-CoV-2 RNA may report low concentration values, leading to artificially increased apparent sensitivity of diagnostic assays [PDF]
, 2020 In response to the rapidly evolving COVID-19 pandemic, the U.S. Food and Drug Administration (FDA) has rapidly issued 49 emergency use authorizations (EUAs) for SARS-CoV-2 in vitro diagnostic test-kits. A critical metric in the performance evaluation for
Ismagilov, Rustem F., Jue, Erik
core +1 more source
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR
BMC Genomics, 2019 Background In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic.
Gemma B. Danks +6 more
doaj +1 more source
BMC Genomics, 2018 Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component of this and yet few rules governing selection are known.
Gemma B. Danks +3 more
doaj +1 more source
One Health, 2021 COVID-19 pandemic has challenged public health systems worldwide, particularly affecting developing countries in Latin America like Ecuador. In this report, we exposed the fundamental role of the Ecuadorian universities to improve COVID-19 surveillance ...
Daniela Santander-Gordon +19 more
doaj +1 more source
Neuronal gene expression in two generations of the marine parasitic worm, Cryptocotyle lingua
Communications Biology, 2023 Trematodes, or flukes, undergo intricate anatomical and behavioral transformations during their life cycle, yet the functional changes in their nervous system remain poorly understood.
Oleg Tolstenkov +2 more
doaj +1 more source
Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. [PDF]
, 2020 BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19).
Fitzgerald, Robert L +5 more
core
Evolution of CDK1 Paralog Specializations in a Lineage With Fast Developing Planktonic Embryos
Frontiers in Cell and Developmental Biology, 2022 The active site of the essential CDK1 kinase is generated by core structural elements, among which the PSTAIRE motif in the critical αC-helix, is universally conserved in the single CDK1 ortholog of all metazoans.
Xiaofei Ma +5 more
doaj +1 more source
Noninvasive mechanical ventilation in high-risk pulmonary infections: a clinical review [PDF]
, 2014 The aim of this article was to review the role of noninvasive ventilation (NIV) in acute pulmonary infectious diseases, such as severe acute respiratory syndrome (SARS), H1N1 and tuberculosis, and to assess the risk of disease transmission with the use ...
Ambrosino, Nicolino +11 more
core +3 more sources
NeuroImage, 2018 At ultra-high fields, the assessment of radiofrequency (RF) safety presents several new challenges compared to low-field systems. Multi-channel RF transmit coils in combination with parallel transmit techniques produce time-dependent and spatially varying power loss densities in the tissue.
Fiedler, Thomas M. +2 more
openaire +4 more sources