Results 61 to 70 of about 1,101,190 (284)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Doublecortin-like kinase is required for cnidocyte development in Nematostella vectensis

open access: yesNeural Development
The complex morphology of neurons requires precise control of their microtubule cytoskeleton. This is achieved by microtubule-associated proteins (MAPs) that regulate the assembly and stability of microtubules, and transport of molecules and vesicles ...
Johanna E. M. Kraus   +4 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

The nascent RNA labelling compound 5-ethynyl uridine (EU) integrates into DNA in some animals

open access: yesBMC Molecular and Cell Biology
Background The detection of de novo synthesized mRNA transcripts is crucial for understanding the regulation of eukaryotic transcription. Using nucleoside or nucleotide analogues to label nascent RNA is potentially jeopardized by the ubiquitous presence ...
Malin A. Kjosavik   +9 more
doaj   +1 more source

Susceptibility and resistance of brook lamprey, Lampetra planeri (Bloch), roach, Rutilus rutilus (L.) and perch, Perca fluviatilis L. to Gyrodactylus salaris Malmberg (Monogenea)

open access: yesFauna Norvegica, 1990
The susceptibility and resistance of brook lamprey, Lampetra planeri, roach Rutilus rutilus and perch, Perca fluviatilis to Gyrodactylus salaris were examined. The level of resistance to the parasite was assessed from counts, made on anaesthetized hosts,
Tor A. Bakke   +2 more
doaj   +1 more source

Manejo de la vía aérea en paciente con diagnóstico de COVID-19

open access: yesSalud Uninorte, 2020
Objetivo: En la presente revisión narrativa se realiza una descripción de las técnicas de manejo de la vía aérea en paciente con diagnóstico de COVID-19.Materiales y métodos: Se realizó una exhaustiva búsqueda bibliográfica en las bases de datos ...
EMILIO ABUABARA-FRANCO   +5 more
doaj   +1 more source

Resultado materno perinatal de las gestantes con infección confirmada por COVID-19, hospital Santa Teresa, Comayagua, Honduras. Serie de casos

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2022
Objetivos: describir el resultado materno y perinatal de las gestantes con infección confirmada por COVID-19 en una institución hospitalaria en Comayagua, Honduras. Materiales y métodos: estudio descriptivo tipo serie de casos.
Alma Iris Zúniga-Briceño   +2 more
doaj   +1 more source

Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong.

open access: yes, 2003
BACKGROUND: Health authorities worldwide, especially in the Asia Pacific region, are seeking effective public-health interventions in the continuing epidemic of severe acute respiratory syndrome (SARS).
Abu-Raddad, Laith J   +18 more
core   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández   +10 more
wiley   +1 more source

Transmission dynamics of the etiological agent of SARS in Hong Kong: impact of public health interventions.

open access: yes, 2003
We present an analysis of the first 10 weeks of the severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The epidemic to date has been characterized by two large clusters-initiated by two separate "super-spread" events (SSEs)-and by ongoing ...
Abu-Raddad, Laith J   +19 more
core   +1 more source

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