Results 211 to 220 of about 24,946,579 (254)

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Association Between Interleukin‐6 Promoter Polymorphisms and Disease Susceptibility: A Review of Current Evidence

iLABMED, EarlyView.
IL‐6 SNPs contribute to the pathogenesis of diverse diseases by altering gene expression, and hold potential as biomarkers for disease risk assessment. ABSTRACT Interleukin 6 (IL‐6), a type of cytokine, plays a role in the onset, progression, and prognosis of various diseases.
Junyi Li, Yiling Xv, Qingfeng Ma, Wei Wang   +3 more
wiley   +1 more source

Heritable transgenic schistosomes as a living platform for SARS-CoV-2 neutralizing antibody secretion. [PDF]

Nat Commun
Ittiprasert W, Smout MJ, Mann VH, Moyle M, Kinahan SM, Ackerman DN, Rivera DN, Santarpia JL, Carnes EC, Mentink-Kane MM, Costa MR, Hokke CH, Roestenberg M, Bottazzi ME, Bracken BK, Rosa BA, Djuranovic S, Pickering DA, Giacomin PR, Watterson D, Modhiran N, Moescheid MF, Grevelding CG, Mitreva M, Loukas A, Brindley PJ.   +25 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source

Antimicrobial peptides as computational candidates for SARS-CoV-2 papain-like protease inhibition. [PDF]

Sci Rep
Dos Santos Moreira E, Siqueira S, Barbosa FS, da Silva Sousa J, Mercado HMP, Melo TS, Jaiswal AK, Azevedo V, Góes-Neto A, Andrade BS.   +9 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Aphasic status epilepticus due to Epstein–Barr virus meningoencephalitis – A clinical vignette

Epileptic Disorders, EarlyView.
Gemma Bassani, Tobias Moser, Lukas Machegger, Fabio Rossini, Georg Pilz, Eugen Trinka, Giorgi Kuchukhidze   +6 more
wiley   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Repurposing screens reveal a role for PKCη and NF1 in SARS-CoV-2 infection. [PDF]

PLoS Pathog
Acuña JA, Miller J, Bhutda S, Ayyanathan K, Kamalia B, Whig K, Nguyen D, Zhu Y, Laleu B, Wells T, Samby K, Pekosz A, Schultz DC, Cherry S.   +13 more
europepmc   +1 more source