Results 41 to 50 of about 331,841 (258)
Comparing South Korea and Italy’s healthcare systems and initiatives to combat COVID-19
Revista Panamericana de Salud Pública, 2020 Italy and South Korea have two distinctly different healthcare systems, causing them to respond to public health crises such as the COVID-19 pandemic in markedly different ways.
Ashwin Palaniappan +2 more
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Rational use of chloroquine and hydroxychloroquine in times of COVID-19
Revista de Ciências Farmacêuticas Básica e Aplicada, 2020 Considering the COVID-19 pandemic declared, part of the researchers' efforts has been in studies of repurposing chloroquine (CQ) and hydroxychloroquine (HCQ), cheap medicines that have been used for decades with indication for malaria, rheumatoid ...
Rosa Camila Lucchetta +1 more
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Wellcome Open Research, 2021 Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not ...
Petra Micochova +5 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
HIV, HSV, SARS-CoV-2 and Ebola Share Long-Term Neuropsychiatric Sequelae
Neuropsychiatric Disease and Treatment, 2022 Pascal Büttiker,1 George B Stefano,1 Simon Weissenberger,2 Radek Ptacek,1 Martin Anders,1 Jiri Raboch,1 Richard M Kream1 1Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech ...
Büttiker P +6 more
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Asthma in the era of SARS CoV-2 virus
Journal of Asthma, 2021 It is well established in international literature that respiratory viruses can trigger asthma exacerbations. However, not all viruses affect patients in the same manner and extent. The pandemic of the SARS CoV-2 virus has brought interest to study the association of this novel virus on patients with mild-moderate and severe asthma in terms of ...
Agamemnon Bakakos, Anastasia Krompa
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
PLoS ONE, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is transmitted mainly by droplet or aerosol infection; however, it may also be transmitted by contact infection.
Masahiro Urushidani +5 more
doaj +1 more source
ACE2: from vasopeptidase to SARS virus receptor [PDF]
Trends in Pharmacological Sciences, 2004 The zinc metallopeptidase angiotensin-converting enzyme 2 (ACE2) is the only known human homologue of the key regulator of blood pressure angiotensin-converting enzyme (ACE). Since its discovery in 2000, ACE2 has been implicated in heart function, hypertension and diabetes, with its effects being mediated, in part, through its ability to convert ...
Turner, Anthony J +2 more
openaire +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source