Results 51 to 60 of about 378,875 (306)

Comparing South Korea and Italy’s healthcare systems and initiatives to combat COVID-19

Revista Panamericana de Salud Pública, 2020
Italy and South Korea have two distinctly different healthcare systems, causing them to respond to public health crises such as the COVID-19 pandemic in markedly different ways.
Ashwin Palaniappan, Udit Dave, Brandon Gosine   +2 more
doaj   +1 more source

A novel hamster model of SARS-CoV-2 respiratory infection using a pseudotyped virus

Scientific Reports, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a biosafety level (BSL)-3 pathogen; therefore, its research environment is limited. Pseudotyped viruses that mimic the infection of SARS-CoV-2 have been widely used for in vitro evaluation ...
Hiroshi Yamada, So-Ichiro Sasaki, Hideki Tani, Mayu Somekawa, Hitoshi Kawasuji, Yumiko Saga, Yoshihiro Yoshida, Yoshihiro Yamamoto, Yoshihiro Hayakawa, Yoshitomo Morinaga   +9 more
doaj   +1 more source

SARS Virus: The Beginning of the Unraveling of a New Coronavirus [PDF]

Journal of Biomedical Science, 2003
Severe acute respiratory syndrome (SARS) virus caused a severe outbreak in several regions of the world in 2003. The virus is a novel coronavirus, which may have an origin in wild animals such as civet cats in southern China. Its genome structure, gene expression pattern and protein profiles are similar to those of other coronaviruses.
openaire   +2 more sources

Rational use of chloroquine and hydroxychloroquine in times of COVID-19

Revista de Ciências Farmacêuticas Básica e Aplicada, 2020
Considering the COVID-19 pandemic declared, part of the researchers' efforts has been in studies of repurposing chloroquine (CQ) and hydroxychloroquine (HCQ), cheap medicines that have been used for decades with indication for malaria, rheumatoid ...
Rosa Camila Lucchetta, Patricia de Carvalho Mastroianni   +1 more
doaj  

Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coating [version 2; peer review: 2 approved]

Wellcome Open Research, 2021
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission occurs via airborne droplets and surface contamination. Titanium dioxide (TiO2) coating of surfaces is a promising infection control measure, though to date has not ...
Petra Micochova, Ambika Chadha, Timi Hesseloj, Franca Fraternali, Jeremy J. Ramsden, Ravindra K. Gupta   +5 more
doaj   +1 more source

ACE2: from vasopeptidase to SARS virus receptor [PDF]

Trends in Pharmacological Sciences, 2004
The zinc metallopeptidase angiotensin-converting enzyme 2 (ACE2) is the only known human homologue of the key regulator of blood pressure angiotensin-converting enzyme (ACE). Since its discovery in 2000, ACE2 has been implicated in heart function, hypertension and diabetes, with its effects being mediated, in part, through its ability to convert ...
Turner, Anthony J, Hiscox, Julian A, Hooper, Nigel M   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

HIV, HSV, SARS-CoV-2 and Ebola Share Long-Term Neuropsychiatric Sequelae

Neuropsychiatric Disease and Treatment, 2022
Pascal Büttiker,1 George B Stefano,1 Simon Weissenberger,2 Radek Ptacek,1 Martin Anders,1 Jiri Raboch,1 Richard M Kream1 1Department of Psychiatry, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech ...
Büttiker P, Stefano GB, Weissenberger S, Ptacek R, Anders M, Raboch J, Kream RM   +6 more
doaj  

Inactivation of SARS-CoV-2 and influenza A virus by dry fogging hypochlorous acid solution and hydrogen peroxide solution.

PLoS ONE, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is transmitted mainly by droplet or aerosol infection; however, it may also be transmitted by contact infection.
Masahiro Urushidani, Akira Kawayoshi, Tomohiro Kotaki, Keiichi Saeki, Yasuko Mori, Masanori Kameoka   +5 more
doaj   +1 more source