Results 51 to 60 of about 54,638 (265)

Quantitative Protein Topography Measurements by High Resolution Hydroxyl Radical Protein Footprinting Enable Accurate Molecular Model Selection

open access: yesScientific Reports, 2017
We report an integrated workflow that allows mass spectrometry-based high-resolution hydroxyl radical protein footprinting (HR-HRPF) measurements to accurately measure the absolute average solvent accessible surface area () of amino acid side chains ...
Boer Xie   +3 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou   +9 more
wiley   +1 more source

CHANGES IN SPATIAL-FUNCTIONAL DEVELOPMENT OF THE MUNICIPALITY OF INĐIJA (SERBIA) [PDF]

open access: yesZbornik Radova: Geografski institut "Jovan Cvijić", 2015
In the municipality of Inđija the influences are very closely connected between the two most populated and economically most important cities in Serbia: Belgrade and Novi Sad.
Radmila Miletić, Marija Drobnjaković
doaj   +2 more sources

Sequence analysis of SasA.

open access: yes, 2016
The full-length amino acid sequence of SasA was analyzed using bioinformatics tools. SasA is mainly composed of a short serine-rich repeat region (SRR1), a non-repeat region (NRR), a second long serine-rich repeat region (SRR2) and a C-terminal cell wall
Shuling Liu (782509)   +11 more
core   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

open access: yesAdvanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun   +18 more
wiley   +1 more source

A review of Tsudayusurika Sasa, 1985 (Diptera: Chironomidae, Orthocladiinae), with the description of a new species

open access: yesFauna Norvegica, 2012
Tsudayusurika Sasa, 1985 is reviewed based on material from Taiwan and Japan. This orthocladiine genus is characterized by having a female antenna with 10 flagellomeres and large and rhombic cerci. The male antenna has 13 flagellomeres and the anal point
Masaru Yamamoto, Nao Yamamoto
doaj   +1 more source

Social Changes and Language Use in the Families of Banat Swabians Between the Two World Wars

open access: yesEtnoantropološki Problemi, 2020
The paper investigates language ideology and language use in the families of Banat Swabians between the two world wars. It is argued that the linguistic practices of the Banat Swabians cannot be understood without insight into the historical context and ...
Aleksandar Krel, Marija Mandić
doaj   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Trends of mean annual and seasonal discharges of rivers in Serbia [PDF]

open access: yesZbornik Radova: Geografski institut "Jovan Cvijić", 2014
Subjects of this paper are trends of annual and seasonal water discharges in Serbia. Data of water discharges at the 94 hydrological stations in the period 1961-2010 were analyzed, using the Mann-Kendall test and Sen's method.
Kovačević-Majkić Jelena   +1 more
doaj   +1 more source

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