Results 91 to 100 of about 1,600,173 (280)

A consumption-based direct tax for countries in transition from socialism [PDF]

open access: yes
This paper suggests a consumption-based direct tax, referred to here as a simplified alternative tax or SAT, as an alternative to the standard income tax for reforming socialist economies (RSEs). The paper consists of seven sections.
McLure, Charles E., Jr.
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Effects of High School Course Taking and SAT Scores On College Major Selection

open access: yesSakarya University Journal of Education, 2013
A survey study design was employed to examine the relationship between enrollment in computer and Advanced Placement courses during high school, SAT scores and subsequent selection of a STEM major in post-secondary education.
Alparslan Şahin   +4 more
doaj  

« Mon compte-rendu n’est que la défense continuée » : étude et analyse des écrits du for privé d’avocats de part et d’autre de la Révolution française à travers l’exemple des Mémoires de Dupin aîné

open access: yesCriminocorpus, 2016
For a long time, studies on lawyers, as for all the socio-professional groups, have been considering mostly the institutional sources, and rarely focused on personal, or even intimate, writings.
Aurore Sat
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Comparing Beliefs, Surveys and Random Walks

open access: yes, 2004
Survey propagation is a powerful technique from statistical physics that has been applied to solve the 3-SAT problem both in principle and in practice.
Aurell, Erik   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An analysis of the Romanian labor market under the impact of the contemporary world’s problems using the regression function [PDF]

open access: yesComputational Methods in Social Sciences, 2015
Having as subject the labor market in the context of the contemporary world’s problems, this paper aims to make a theoretical and practical presentation of these concepts, which are relevant for the national and international literature.
Constanţa Popescu   +2 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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