Results 111 to 120 of about 1,698,061 (303)
An analysis of the Romanian labor market under the impact of the contemporary world’s problems using the regression function [PDF]
Computational Methods in Social Sciences, 2015 Having as subject the labor market in the context of the contemporary world’s problems, this paper aims to make a theoretical and practical presentation of these concepts, which are relevant for the national and international literature.
Constanţa Popescu +2 more
doaj
Comparing Beliefs, Surveys and Random Walks
, 2004 Survey propagation is a powerful technique from statistical physics that has been applied to solve the 3-SAT problem both in principle and in practice.
Aurell, Erik +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
From Parallel SAT to Distributed SAT
EPiC Series in Computing, 2018 This tutorial will present an overview of parallelism in SAT. It will start with a presentation of classical divide and conquer techniques, discuss their ancient origin and compare them to more recent portfolio- based algorithms. It will then present the impact of clause-sharing on their performances and discuss various strategies used to control the ...
openaire +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2012 This paper presents the result on existence, uniqueness of mild solutions to neutral stochastic partial functional integrodifferential equations under the Carathéodory-type conditions on the coefficients.
Mamadou Abdoul Diop +2 more
doaj +1 more source