Results 61 to 70 of about 246,520 (298)

Benchmark of quantum-inspired heuristic solvers for quadratic unconstrained binary optimization

open access: yesScientific Reports, 2022
Recently, inspired by quantum annealing, many solvers specialized for unconstrained binary quadratic programming problems have been developed. For further improvement and application of these solvers, it is important to clarify the differences in their ...
Hiroki Oshiyama, Masayuki Ohzeki
doaj   +1 more source

fbSAT: Automatic Inference of Minimal Finite-State Models of Function Blocks Using SAT Solver

open access: yesIEEE Access, 2022
Finite-state models are widely used in software engineering, especially in the development of control systems. In control applications, such models are often developed manually, which can make it difficult to keep them up to date.
Konstantin Chukharev, Daniil Chivilikhin
doaj   +1 more source

A better algorithm for random k-SAT [PDF]

open access: yes, 2009
Let Φ be a uniformly distributed random k-SAT formula with n variables and m clauses. We present a polynomial time algorithm that finds a satisfying assignment of Φ with high probability for constraint densities m/n < (1 − εk)2k ln(k)/k, where εk → 0 ...
Coja-Oghlan, Amin, Amin Coja-Oghlan
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

SMT Attack: Next Generation Attack on Obfuscated Circuits with Capabilities and Performance Beyond the SAT Attacks

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2018
In this paper, we introduce the Satisfiability Modulo Theory (SMT) attack on obfuscated circuits. The proposed attack is the superset of Satisfiability (SAT) attack, with many additional features.
Kimia Zamiri Azar   +3 more
doaj   +1 more source

The Configurable SAT Solver Challenge (CSSC)

open access: yesArtificial Intelligence, 2017
It is well known that different solution strategies work well for different types of instances of hard combinatorial problems. As a consequence, most solvers for the propositional satisfiability problem (SAT) expose parameters that allow them to be customized to a particular family of instances.
Frank Hutter   +5 more
openaire   +6 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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