Results 51 to 60 of about 1,329,786 (260)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Satellite knots and L-space surgeries [PDF]

, 2016
We give sufficient conditions for a satellite knot to admit an L-space surgery, and use this result to give new infinite families of patterns which produce satellite L-space knots.
arxiv   +1 more source

Satellite-based sunshine duration for Europe [PDF]

, 2013
In this study, two different methods were applied to derive daily and monthly sunshine duration based on high-resolution satellite products provided by the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT) Satellite ...
Almorox, André Obregón, Bodo Ahrens, Dolinar, Döll, Elizabeth Good, Ertekin, Essa, Good, Helga Nitsche, Hogewind, Jhajharia, Journée, Kandirmaz, Lam, Monteith, Moradi, Mueller, New, Ohmura, Raichijk, Sanchez-Lorenzo, Sanchez-Lorenzo, Skartveit, Steffen Kothe, Tang, Wild, Ångström   +27 more
core   +4 more sources

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration. [PDF]

, 2010
Satellite cells are skeletal muscle stem cells capable of self-renewal and differentiation after transplantation, but whether they contribute to endogenous muscle fiber repair has been unclear.
Basson, M Albert, Brack, Andrew S, Keller, Charles, LaPorta, Vincent S, Licht, Jonathan D, Shea, Kelly L, Xiang, Wanyi   +6 more
core   +3 more sources

Satellite-to-Satellite Tracking and Satellite Gravity Gradiometry [PDF]

, 2001
The purpose of satellite-to-satellite tracking (SST) and/or satellite gravity gradiometry (SGG) is to determine the gravitational field on and outside the Earth's surface from given gradients of the gravitational potential and/or the gravitational field at satellite altitude.
Freeden, Willi, Michel, Volker, Nutz, Helga   +2 more
openaire   +1 more source

Monte Carlo modeling of radiation dose from radiation therapy with superficial x‐rays

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Superficial x‐rays (50–100 kVp) are used for treating non‐melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly increases absorbed dose to bone compared to soft tissue.
Reham Barghash, Tiffany W. Martin, Amber R. Prebble, Del Leary   +3 more
wiley   +1 more source

Ethnoracial disparities in gray matter atrophy are mediated by structural disconnectivity in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 615-630, March 2025.
This study aimed to assess gray matter (GM) atrophy, the contribution of white matter (WM) lesions, and consequent structural disconnectivity in minority patients with multiple sclerosis (PwMS). Minority PwMS were found to have greater lesion burden and GM atrophy. Differences in GM atrophy were partially mediated by WM pathology. Abstract Objective To
Ahmed Bayoumi, Joseph A. Thomas, Breanna R. Alonzo, Juan Jimenez, Christopher M. Orlando, Carlos A. Pérez, Khader M. Hasan, Jerry S. Wolinsky, John A. Lincoln   +8 more
wiley   +1 more source

Amplification and adaptation of centromeric repeats in polyploid switchgrass species. [PDF]

, 2018
Centromeres in most higher eukaryotes are composed of long arrays of satellite repeats from a single satellite repeat family. Why centromeres are dominated by a single satellite repeat and how the satellite repeats originate and evolve are among the most
Braz, Guilherme T, Casler, Michael D, Han, Yonghua, Jiang, Jiming, Schmutz, Jeremy, Yang, Xueming, Zeng, Zixian, Zhang, Pingdong, Zhang, Tao, Zhao, Hainan, Zhu, Bo   +10 more
core   +2 more sources