Results 91 to 100 of about 30,945 (217)

Incorporation of Satellite Precipitation Uncertainty in a Landslide Hazard Nowcasting System. [PDF]

J Hydrometeorol, 2020
Hartke SH, Wright DB, Kirschbaum DB, Stanley TA, Li Z.   +4 more
europepmc   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

On the Propagation of Satellite Precipitation Estimation Errors: From Passive Microwave to Infrared Estimates. [PDF]

J Hydrometeorol, 2020
Upadhyaya SA, Kirstetter PE, Gourley JJ, Kuligowski RJ.   +3 more
europepmc   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

PERSIANN Dynamic Infrared-Rain Rate (PDIR-Now): A Near-Real-Time, Quasi-Global Satellite Precipitation Dataset. [PDF]

J Hydrometeorol, 2020
Nguyen P, Ombadi M, Gorooh VA, Shearer EJ, Sadeghi M, Sorooshian S, Hsu K, Bolvin D, Ralph MF.   +8 more
europepmc   +1 more source

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

Advanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua, Shuang Pang, Ang Li, Zonghao Hu, Honghui Wu, Shuhan Zhang, Yi Fan, Yi Wu, Wei Yang, Yachao Zhao, Yupeng Guan, Baoming Ji, Deliang Kong, Yong Zhao, Anton A. Goncharov, Anastasia Yu. Korotkevich, Rong Mao, Yang Zhang, Ximei Zhang   +18 more
wiley   +1 more source

Assessment of CHIRPS and PERSIANN-CDR products for meteorological drought monitoring and future trends in East Africa

Environmental Research: Climate
The satellite precipitation products provide a reliable alternative data source for real-time drought monitoring in developing countries. Therefore, it is important to quantify the excellent satellite precipitation products for drought estimation.
Priyanko Das, Suravi Ghosh, Zhenke Zhang, Shouming Feng   +3 more
doaj   +1 more source

Very high resolution, altitude-corrected, TMPA-based monthly satellite precipitation product over the CONUS. [PDF]

Sci Data, 2020
Hashemi H, Fayne J, Lakshmi V, Huffman GJ.   +3 more
europepmc   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

Advanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias, Carmen Domínguez‐Alonso, Ivana Zagorac, Antonio Tapia‐Galisteo, Eva García‐Veros, Laura Rubio‐Pérez, Marina Gómez‐Rosel, Patricia Fuentes, Patricia Hernández‐López, Óscar Aguilar‐Sopeña, Laura Almagro‐Puente, Sonia Martínez‐González, Lucía Cañizares‐Moscato, María Rivas‐Sánchez, Belén Blanco, Ángel Ramírez‐Fernández, Laura Díez‐Alonso, Carmen Blanco‐Aparicio, Javier Arroyo‐Ródenas, Jorge Martínez‐Torrecuadrada, María L. Toribio, Pedro Roda‐Navarro, Anaïs Jiménez‐Reinoso, Luis Álvarez‐Vallina   +23 more
wiley   +1 more source

Regional-scale intelligent optimization and topography impact in restoring global precipitation data gaps

Communications Earth & Environment
Ground rainfall observations are essential for improving gauge-adjusted satellite precipitation estimates, particularly in the Global Precipitation Measurement mission era.
Jiahan Wang, Jiaqi Chen, Peng Shen, Xiaoling Guan, Xiangmei Liu, Christian Massari, Zongzhi Wang, Mingming Feng, Qingxuan Wang, Youbei Lu, Ersa Wei, Yonghao Wang, Gulomjon Umirzakov, Bin Yong   +13 more
doaj   +1 more source