Results 141 to 150 of about 109,215 (308)

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

open access: yesObesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo   +4 more
wiley   +1 more source

Addition of Phentermine‐Topiramate to a Digitally Enhanced Lifestyle Intervention: A Double‐Blind Randomized Clinical Trial

open access: yesObesity, EarlyView.
ABSTRACT Objective This study compared the effects of phentermine‐topiramate‐ER (mid‐dose 7.5/46 mg) versus placebo on weight loss and cardiovascular disease (CVD) risk outcomes when used as an adjunct to a digitally enhanced lifestyle intervention (DELI).
Alejandro Campos   +15 more
wiley   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

open access: yesObesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden   +6 more
wiley   +1 more source

A paradigm shift for the prevention and treatment of individual and global obesity

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2018
Arnold H Slyper Clalit Health Organization, Jerusalem 9514622, Israel Abstract: The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase.
Slyper AH
doaj  

Resource limitation and competition shape reproductive allocation and synchrony

open access: yesOikos, EarlyView.
The dynamics of reproductive allocation (RA) in herbaceous plant communities, particularly in response to varying environmental conditions such as drought stress and competitive interactions, remain underexplored. This study aims to fill this gap by hypothesising that both belowground resource limitation and the presence of dominant species ...
Jan Douda   +2 more
wiley   +1 more source

Multiple scales of fear: foraging behaviour of white‐naped jays in semiarid landscapes

open access: yesOikos, EarlyView.
Animals must constantly balance the need to find resources with the risk of predation. Not only avoiding direct encounters with predators but also assessing the overall risk of their environment using cues, social information or habitat traits at multiple spatial and temporal scales.
Maria Carolina Beiriz   +2 more
wiley   +1 more source

GLP‐1 Receptor Agonists for Obstructive Sleep Apnea: An Otolaryngologist's Prescription?

open access: yes
The Laryngoscope, EarlyView.
Alina Zgardau   +3 more
wiley   +1 more source

Bioclimatic, demographic and anthropogenic correlates of grizzly bear activity patterns in the Greater Yellowstone Ecosystem

open access: yesOikos, EarlyView.
Plasticity of diel activity rhythms may be a key element for adaptations of wildlife populations to changing environmental conditions. In the last decades, grizzly bears Ursus arctos in the Greater Yellowstone Ecosystem (GYE) have experienced notable environmental fluctuations, including changes in availability of food sources and severe droughts ...
Aurora Donatelli   +4 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Deep Proteomic Profiles of the Antarctic Diatom Fragilariopsis Cylindrus Under Varying Iron and Manganese Conditions

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre   +3 more
wiley   +1 more source

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