Results 141 to 150 of about 109,215 (308)
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo +4 more
wiley +1 more source
ABSTRACT Objective This study compared the effects of phentermine‐topiramate‐ER (mid‐dose 7.5/46 mg) versus placebo on weight loss and cardiovascular disease (CVD) risk outcomes when used as an adjunct to a digitally enhanced lifestyle intervention (DELI).
Alejandro Campos +15 more
wiley +1 more source
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden +6 more
wiley +1 more source
A paradigm shift for the prevention and treatment of individual and global obesity
Arnold H Slyper Clalit Health Organization, Jerusalem 9514622, Israel Abstract: The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of the world, it continues to increase.
Slyper AH
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Resource limitation and competition shape reproductive allocation and synchrony
The dynamics of reproductive allocation (RA) in herbaceous plant communities, particularly in response to varying environmental conditions such as drought stress and competitive interactions, remain underexplored. This study aims to fill this gap by hypothesising that both belowground resource limitation and the presence of dominant species ...
Jan Douda +2 more
wiley +1 more source
Multiple scales of fear: foraging behaviour of white‐naped jays in semiarid landscapes
Animals must constantly balance the need to find resources with the risk of predation. Not only avoiding direct encounters with predators but also assessing the overall risk of their environment using cues, social information or habitat traits at multiple spatial and temporal scales.
Maria Carolina Beiriz +2 more
wiley +1 more source
GLP‐1 Receptor Agonists for Obstructive Sleep Apnea: An Otolaryngologist's Prescription?
The Laryngoscope, EarlyView.
Alina Zgardau +3 more
wiley +1 more source
Plasticity of diel activity rhythms may be a key element for adaptations of wildlife populations to changing environmental conditions. In the last decades, grizzly bears Ursus arctos in the Greater Yellowstone Ecosystem (GYE) have experienced notable environmental fluctuations, including changes in availability of food sources and severe droughts ...
Aurora Donatelli +4 more
wiley +1 more source
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
ABSTRACT Fragilariopsis cylindrus is a key diatom in the Southern Ocean, where low iron and manganese availability constrain primary production and biogeochemical activity. The molecular mechanisms used by polar diatoms, including F. cylindrus, to cope with trace metal limitations remain largely unexplored.
Loay J. Jabre +3 more
wiley +1 more source

