Results 61 to 70 of about 9,433,825 (271)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Distribution and flow of methane and water in kaolinite nanoslits [PDF]

AIP Advances
Inorganic mineral pores in coal are highly effective conduits for the transport of methane and water but are primary sites for water blocking. Current research on methane/water two-phase flow in coal focuses on pores in organic matter, and few studies ...
Yafei Luo, 罗亚飞, Zhangkai Zheng, 郑张凯, Huarui Hu, 胡华瑞, Qiangwei Lin, 林强伟, Fei Huang, 黄飞, Pengfei Wang, 王鹏飞   +11 more
doaj   +1 more source

Study on the influence of physical interlayers on the remaining oil production under different development modes

Open Chemistry, 2022
Using the complex stratigraphic structure model, we study the changes in remaining oil on the millimeter scale in different structural parts during the different water flooding development methods.
Yu Zhao, Wenguo Ma, Qinglong Du, Qiang Xu, Zengzhi Li, Ruilin Ma, Qi Chen   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

An Analysis of the Interactions between Adjustment Factors of Saturation Flow Rates at Signalized Intersections

, 2020
An insufficient functional relationship between adjustment factors and saturation flow rate (SFR) in the U.S. Highway Capacity Manual (HCM) method increases an additional prediction bias. The error of SFR predictions can reach 8–10%.
Yi Wang, J. Rong, Chen-Jing Zhou, Xin Chang, Si-Yang Liu   +4 more
semanticscholar   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Operational Efficiency Evaluation of Intersections with Dynamic Lane Assignment Using Field Data

Journal of Advanced Transportation, 2017
The dynamic lane assignment at signalized intersections is a possible countermeasure to address the traffic demand variability problem. However, the operational efficiency is affected by the unfamiliarity of the drivers.
Jing Zhao, Jiao Yao, Shengxue He, Yin Han   +3 more
doaj   +1 more source

Modeling and optimization of oil refinery wastewater chemical oxygen demand removal in dissolved air flotation system by response surface methodology [PDF]

Advances in Environmental Technology, 2015
In this present study the dissolved air flotation (DAF) system was investigated for the treatment of Kermanshah Oil Refinery wastewater. The effect of three parameters on flotation efficiency including of flow rate (outflow from the flotation tank ...
yasser vasseghian
doaj   +1 more source

Estimation of Saturation Flow Rate and Start-Up Lost Time for Signal Timing Based on Headway Distribution

, 2015
This study aimed to calibrate saturation flow rate (SFR) and start-up lost time (SLT) when developing signal timing. In current commonly used methods, SFR for one given lane is usually calibrated from many subjective adjustment factors and a fixed result.
Yi Zhao, Wen-Bo Zhang, Jian Lu, Wen-Jun Zhang, Yong-Feng Ma   +4 more
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source