Results 111 to 120 of about 1,572,455 (316)

The Population’ Income, Expenses and Savings as Descriptive Aspects of the Standard of Living [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
At the level of any society, the income, expenses and savings have been playing and continue toplay an important role from both macroeconomic perspective (as a key element in the developmentof a company) and microeconomic perspective (from the point of ...
Mălina-Ionela Burlacu
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The HIV Anticaptory Saving Motive: An Empirical Analysis in South Africa [PDF]

open access: yes
This paper studies the effect of the HIV/AIDS epidemic on saving behaviour. Two important characteristics of HIV result in opposing forces on savings: mortality increases, which reduces savings, and long-term illness risk increases, which enhances ...
Kuilen, G. van de, Lammers, J.
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Self-control and savings [PDF]

open access: yes
We reconsider the well-established paradigm of a rational individual's choice of a consumption schedule, building on the idea that human beings devote resources to withstand their desire for immediate consumption, i.e.
Michel, Philippe, Vidal, Jean-Pierre
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Importance of Default Options for Retirement Savings Outcomes: Evidence from the United States [PDF]

open access: yes
This paper summarizes the empirical evidence on how defaults impact retirement savings outcomes. After outlining the salient features of the various sources of retirement income in the U.S., the paper presents the empirical evidence on how defaults ...
Brigitte C. Madrian   +3 more
core  

Understanding Early Withdrawals From Retirement Accounts [PDF]

open access: yes, 2010
Examines early withdrawals from IRAs and 401(k)s by demographics, education, income, and reason, including job loss, poor health, and college costs.
Barbara A. Butrica   +2 more
core  

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