Results 141 to 150 of about 1,568,597 (315)

In the Red or In the Black?: Understanding the Relationship Between Household Debt and Assets [PDF]

open access: yes, 2008
In the Red or In the Black? looks at whether household savings serve to protect families from incurring unsecured debt, and in turn, whether the presence of unsecured debt acts as a barrier to savings and wealth ...
Jose Garcia
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Demographic Change and the UK Savings Rate [PDF]

open access: yes
We use microeconomic data to explore the effects of a changing age-structure on the UK's aggregate personal savings rate. Our findings suggest that changes to the population's age structure age have had detectable, sustained, but, relative to the yearly ...
David Demery, Nigel Duck
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Save Reginald! Save Tidemill!

open access: yes, 2018
This short article describes the work of the Save Reginald! Save Tidemill! Campaign in Deptford and how they tried to save Tidemill Garden and Reginald House, a council block next to the garden. Documenting their activities was part of my PhD research.
openaire  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Saving faces [PDF]

open access: yesCanadian Medical Association Journal, 2018
openaire   +2 more sources

The Ageing, Longevity and Crowding Out Effects on Private and Public Savings: Evidence from Dynamic Panel Analysis [PDF]

open access: yes
Life-cycle theory predicts ageing exerting long-term macroeconomic impacts through the reduction of private savings. Ageing can be brought either through a fall in fertility rates or a rise in longevity. However, empirical research studying macroeconomic
Benjamin ShiJie Wong, Kam-Ki Tang
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Savings Behaviour in the Indian Economy [PDF]

open access: yes
An attempt has been made in the present exercise to examine the savings behaviour in the Indian Economy in terms of shift in the growth rates of domestic savings, and in magnitude of income elasticity of the domestic savings at the aggregate and ...
Reddy, N.L., Upender, M.
core  

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