Results 201 to 210 of about 175,859 (268)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Ocular oncology: Saving sight, saving lives

Middle East African Journal of Ophthalmology, 2018
openaire   +3 more sources

Budget impact of expanded hemodialysis versus high-flux hemodialysis using real-world evidence in Colombia. [PDF]

Cost Eff Resour Alloc
Sanabria M, Vesga J, Rivera A, Rutherford P, Quitian H, Lindholm B.   +5 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Building energy retrofits in Canada under government fiscal constraints. [PDF]

Sci Rep
Madadizadeh A, Siddiqui K, Aliabadi AA.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

The Oncology Care Model and Initiation of Systemic Therapy for Cancer. [PDF]

JAMA Intern Med
Keating NL, Lam MB, Landrum MB, McWilliams JM, Wright AA, Brooks GA, Zubizarreta JR, Buzzee B, Landon BE.   +8 more
europepmc   +1 more source

Market and welfare effects of a nationwide sugar-sweetened beverage tax in the U.S. [PDF]

Front Public Health
Lee Y, Giannakas K.
europepmc   +1 more source

Factors contributing to resilience amongst adolescent girls in artisanal and small-scale mining communities in Ghana and Uganda. [PDF]

Health Psychol Behav Med
Chidwick H, Kwagala B, John Bosco A, Nahela N, Kapiriri L.   +4 more
europepmc   +1 more source

The Clinical and Economic Value of Incorporating Monocyte Distribution Width Testing in the Detection of Occult Sepsis. [PDF]

J Health Econ Outcomes Res
Das L, Naiman M, Radcliff J, Sullivan Lofstrom MA, Schwartz S, Saeedian M, Ngantung W, Mirza S.   +7 more
europepmc   +1 more source