Results 201 to 210 of about 52,949 (260)

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

AlphaFold distillation for inverse protein design. [PDF]

Sci Rep
Melnyk I, Lozano A, Das P, Chenthamarakshan V.   +3 more
europepmc   +1 more source

Distinct Tryptase Gene Copy Number Variations Correlate With Tryptase Levels in a Population‐Based Cohort

Allergy, EarlyView.
Yannick Chantran, Simone Choi, Céline Roda, Stéphane Barete, Pierre Hirsch, Olivier Hermine, Laura Polivka, Julien Rossignol, Michel Arock, Fanny Rancière, Isabelle Momas   +10 more
wiley   +1 more source

The Dual Immunoregulatory Role of CREB3L1 Underlying Latent and Severe Tuberculosis Clinical Manifestation

Immunology, EarlyView.
RNA‐seq of lungs and livers from Mycobacterium tuberculosis‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and ...
Felipe T. Lima, Ricardo C. Castro, Francisco R. Javier, Caroline Fontanari, Valdes R. Bollela, Rogerio S. Rosada, Célio L. Silva, Lúcia H. Faccioli, Luiz G. Gardinassi, Fabiani G. Frantz   +9 more
wiley   +1 more source

Stimulus representations in visual cortex shaped by spatial attention and microsaccades. [PDF]

Proc Natl Acad Sci U S A
Srinivasan K, Lowet E, Gomes B, Desimone R.   +3 more
europepmc   +1 more source

The tympanic covering layer contributes to basilar membrane elasticity potentially influencing human frequency resolution and speech perception

Journal of Anatomy, EarlyView.
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu, Claudia Steinacher, Alexander Glueckert, Rudolf Glueckert, Hao Li, Karin Staxäng, Anneliese Schrott‐Fischer, Hanif M. Ladak, Sumit Agrawal, Helge Rask‐Andersen   +9 more
wiley   +1 more source

Predicting breast cancer treatment response and prognosis using AI-based image classification. [PDF]

Front Oncol
Wang B, Chen S, Li W.
europepmc   +1 more source

Predicting Malignant Transformation in Oral Leukoplakia: A Multilayer Perceptron Approach Incorporating Clinicopathological Features and DNA Content

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral leukoplakia (OL) is a potentially malignant disorder of the oral mucosa. Accurate prediction of malignant transformation (MT) remains a clinical challenge. This study aimed to develop and evaluate a machine learning model that integrates histopathological, demographic, and DNA content features to predict MT risk in OL.
Guilherme Iani Pontes, Anna Luíza Damaceno Araújo, Andresa Borges Soares, Saman Warnakulasuriya, André Luis Santana de Freitas, Caroline Gennari Stevão, Marcelo Sperandio, Matheus Cardoso Moraes   +7 more
wiley   +1 more source

Multiplexing of cognitive encoding by oculomotor networks leads to incidental gaze shifts. [PDF]

Proc Natl Acad Sci U S A
Rosen MC, Freedman DJ.
europepmc   +1 more source

Reading versus listening: Which one is more effective for incidental vocabulary learning?

The Modern Language Journal, EarlyView.
Abstract The article examines incidental vocabulary acquisition, focusing on the differential impacts of input modalities—reading versus listening—on learning of single words and multi‐word expressions. Eighty‐eight university students of L2 Italian were assigned to one of the three groups: (a) reading half of an authentic Italian novel, (b) listening ...
Mahnaz Aliyar, Anna Siyanova‐Chanturia, Stephen Skalicky   +2 more
wiley   +1 more source