Results 51 to 60 of about 49,797 (259)

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

open access: yesAnnals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto   +12 more
wiley   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

open access: yesAnnals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato   +7 more
wiley   +1 more source

Combining ability analysis for yield and its component traits in sesame (Sesamum indicum L)

open access: yesElectronic Journal of Plant Breeding, 2017
Combining ability analysis was carried out in 8 x 8 half diallel mating system for ten quantitative characters in sesame (Sesamum indicum L). The present study revealed the importance of both additive as well as non-additive genetic components for ...
S. D. Rajput, P.N. Harer and, N.S. Kute
doaj   +1 more source

PbAT: A user‐friendly R/Shiny platform for data‐driven decision support in crop improvement

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Premise Modern plant breeding requires robust analysis of complex, multi‐environment datasets to identify superior genotypes. Although R offers powerful statistical packages, their use often requires programming expertise. Existing graphical user interface (GUI)‐based tools are either limited in scope or not openly accessible, leaving breeders
Krishnan P. Abhijith   +6 more
wiley   +1 more source

MicroCT reinvestigation of the only articulated fossil anostomid fish reveals synonymy of Arhinolemur Ameghino, 1898 and Megaleporinus Ramirez et al., 2017

open access: yesThe Anatomical Record, EarlyView.
Abstract Arhinolemur scalabrinii† Ameghino, 1898 was originally described as a strepsirrhine primate (Mammalia) but has been recognized as an anostomid fish since 2012. It remains the only extinct anostomid species known from complete cranial material.
Karen M. Panzeri   +8 more
wiley   +1 more source

Exploring Heterosis in Melon (Cucumis melo L.)

open access: yesPlants, 2020
Heterosis is the superiority of an F1 hybrid over its parents. Since this phenomenon is still unclear in melon, a half diallel experiment based on eight genetically distant breeding lines was conducted in six environments of Central Italy, assessing ...
Marco Napolitano   +5 more
doaj   +1 more source

Integrated microanatomy and microstructure of the maxillary tooth plate reveal a reinforced feeding system and tougher diet in Late Triassic Hyperodapedontinae (Rhynchosauria, Archosauromorpha)

open access: yesThe Anatomical Record, EarlyView.
Abstract Hyperodapedontine rhynchosaurs possessed a unique oral apparatus, long interpreted as an adaptation for processing abrasive and resistant plant material. However, the microanatomical and histological evidence supporting this interpretation remains poorly documented.
Caio A. Scartezini   +3 more
wiley   +1 more source

Combining ability analysis for yield and yield component traits in finger millet (Eleusine coracana (L.) Gaertn.) [PDF]

open access: yesElectronic Journal of Plant Breeding, 2010
An experiment was conducted to estimate the gca and sca effects for yield and yield attributing traits in fingermillet. In the present investigation, the parents were mated in half diallel mating design.
C. Priyadharshini, A. Nirmalakumari and A. John Joel
doaj  

A Geomorphometric Approach to Estimate the Deterioration of Earthen Archaeological Sites by Rainfall and Diffusion Processes: The Huaca Chornancap (Eighth–14th Century ad), Lambayeque, Peru

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Rain‐induced erosion processes can severely damage Earthen archaeological sites. Huaca Chornancap (HCH; eighth–14th century ad) is a platform located in the Lambayeque region (Peru) exposed to seasonal rain due to El Niño Southern Oscillation (ENSO).
Luigi Magnini   +5 more
wiley   +1 more source

Combining ability analysis for grain yield and quality traits in pearl millet [Pennisetum glaucum (L.) R. Br.]

open access: yesElectronic Journal of Plant Breeding, 2017
Combining ability analysis performed using 15 parental lines and their 54 hybrids in pearl millet in L x T mating design. The magnitude of SCA variances was higher than the GCA variances for all the characters, which indicated predominance of non ...
Priyanka Solanki   +3 more
doaj   +1 more source

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