Results 81 to 90 of about 282,431 (293)

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

open access: yesAdvanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman   +15 more
wiley   +1 more source

Exploring Heterosis in Melon (Cucumis melo L.)

open access: yesPlants, 2020
Heterosis is the superiority of an F1 hybrid over its parents. Since this phenomenon is still unclear in melon, a half diallel experiment based on eight genetically distant breeding lines was conducted in six environments of Central Italy, assessing ...
Marco Napolitano   +5 more
doaj   +1 more source

Redefining A in RGBA: Towards a Standard for Graphical 3D Printing [PDF]

open access: yes, 2019
Advances in multimaterial 3D printing have the potential to reproduce various visual appearance attributes of an object in addition to its shape. Since many existing 3D file formats encode color and translucency by RGBA textures mapped to 3D shapes, RGBA
Brunton, Alan   +4 more
core   +2 more sources

Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity

open access: yesAdvanced Science, EarlyView.
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao   +11 more
wiley   +1 more source

Comprehensive assessment of combining ability and heterosis for the development of superior three-line hybrids in rice (Oryza sativa L.)

open access: yesElectronic Journal of Plant Breeding
The present study involved assessment of 70 three-line hybrids obtained by crossing five CMS lines and 14 testers using line x tester mating design for combining ability and heterosis for 13 yield and grain quality traits.
R. Nivedha1, S. Manonmani1*, T.Kalaimagal2, M. Raveendran3 and S. Kavitha4
doaj   +1 more source

Survival Probability in Patients with Sickle Cell Anemia Using the Competitive Risk Statistical Model. [PDF]

open access: yes, 2019
The clinical picture of patients with sickle cell anemia (SCA) is associated with several complications some of which could be fatal. The objective of this study is to analyze the causes of death and the effect of sex and age on survival of Brazilian ...
Ballas, Samir K.   +3 more
core   +1 more source

PEC‐DFM Hybrid‐Sensor Based on Nanoparticle‐Resolved Estimation for Sensitive and Reversible Glucose Monitoring

open access: yesAdvanced Science, EarlyView.
Abstract The accurate detection of glucose in wound exudate is critically important for monitoring chronic wound healing. While photoelectrochemical (PEC) sensors are widely used, they often suffer from material degradation caused by redox reactions during operation. Herein, we introduce a dark‐field microscopy (DFM) setup integrated with a PEC system,
Zihao Zhang   +7 more
wiley   +1 more source

Combining ability analysis for grain yield and quality traits in pearl millet [Pennisetum glaucum (L.) R. Br.]

open access: yesElectronic Journal of Plant Breeding, 2017
Combining ability analysis performed using 15 parental lines and their 54 hybrids in pearl millet in L x T mating design. The magnitude of SCA variances was higher than the GCA variances for all the characters, which indicated predominance of non ...
Priyanka Solanki   +3 more
doaj   +1 more source

The case for building climate reporting into financial accounting [PDF]

open access: yes, 2019
For mitigation efforts against climate breakdown to be effective they need to bring in the private sector in a meaningful way. Current standards for financial reporting for commercial organizations focus on the interests of capital suppliers to the ...
Murphy, R., Seabrooke, L.
core  

Protein sectors: statistical coupling analysis versus conservation

open access: yes, 2014
Statistical coupling analysis (SCA) is a method for analyzing multiple sequence alignments that was used to identify groups of coevolving residues termed "sectors".
Colwell, Lucy J.   +2 more
core   +4 more sources

Home - About - Disclaimer - Privacy