Results 11 to 20 of about 2,429 (159)
Force dysmetria in spinocerebellar ataxia 6 correlates with functional capacity [PDF]
Frontiers in Human Neuroscience, 2015 Spinocerebellar ataxia type 6 (SCA6) is a genetic disease that causes pure cerebellar degeneration affecting walking, balance, and coordination. One of the main symptoms of SCA6 is dysmetria.
Agostina eCasamento Moran +6 more
doaj +2 more sources
Cadmium Accumulation in Cacao Plants (Theobroma cacao L.) under Drought Stress
Agronomy, 2023 The objective of this study was to determine Cd accumulation under water-deficit conditions by young cacao plants. The study was conducted under greenhouse conditions.
Antonio Ortiz-Álvarez +5 more
doaj +1 more source
Stem Cell Research, 2020 Spinocerebellar ataxia type 6 (SCA6) is an autosomal dominant hereditary disease caused by repeated CAG amplification in the CACNA1A gene. There is no specific treatment for SCA6, and the currently administered treatment is mainly symptomatic.
Ting Yang +11 more
doaj +1 more source
Open Life Sciences, 2023 Neurologists have a difficult time identifying sporadic cerebellar ataxia. Multiple system atrophy of the cerebellar type (MSA-C), spontaneous late cortical cerebellar atrophy, and prolonged alcohol use are a few possible causes.
Peng Yufen +4 more
doaj +1 more source
Clinical value of vestibulo-ocular reflex in the differentiation of spinocerebellar ataxias
Scientific Reports, 2023 The diagnosis of spinocerebellar ataxia (SCA) currently depends upon genetic testing. Although genetic testing for SCA is highly specific, clinical parameters for the differentiation of SCAs are still insufficient. We aimed to assess the vestibulo-ocular
Jae-Myung Kim +4 more
doaj +1 more source
Frontiers in Neuroscience, 2022 BackgroundIn spinocerebellar ataxia type 3 (SCA3), volume loss has been reported in the basal ganglia, an iron-rich brain region, but iron content has not been examined.
Cherie L. Marvel +11 more
doaj +1 more source
Genetic Screening for Spinocerebellar Ataxia Genes in a Japanese Single-Hospital Cohort [PDF]
Journal of Movement Disorders, 2017 Objective Diagnosis of sporadic cerebellar ataxia is a challenge for neurologists. A wide range of potential causes exist, including chronic alcohol use, multiple system atrophy of cerebellar type (MSA-C), and sporadic late cortical cerebellar atrophy ...
Ryuji Sakakibara +9 more
doaj +1 more source
Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects of a single mutation. [PDF]
, 2015 Spinocerebellar Ataxia type 6 (SCA6) is an autosomal dominant neurodegenerative disease characterized by late onset, slowly progressive, mostly pure cerebellar ataxia. It is one of three allelic disorders associated to CACNA1A gene, coding for the Alpha1
Veneziano, L +11 more
core +1 more source
Vestibular Performance During High-Acceleration Stimuli Correlates with Clinical Decline in SCA6 [PDF]
, 2015 In spinocerebellar ataxia type 6 (SCA6), the vestibular dysfunction and its correlation with other clinical parameters require further exploration. We determined vestibular responses over a broad range of stimulus acceleration in 11 patients with SCA6 ...
Huh, Young Eun +7 more
core +2 more sources
Spinocerebellar ataxia type 6 (SCA6): neurodegeneration goes beyond the known brain predilection sites. [PDF]
, 2009 Contains fulltext : 81519.pdf (Publisher’s version ) (Closed access)AIMS: Spinocerebellar ataxia type 6 (SCA6) is a late onset autosomal dominantly inherited ataxic disorder, which belongs to the group of CAG repeat, or polyglutamine ...
Rueb, U. +20 more
core +1 more source