Results 151 to 160 of about 346,909 (265)
Advanced Healthcare Materials, EarlyView.We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach +4 more
wiley +1 more source
Dual-Functional Triphasic Composite Scaffolds for Enhanced Antibacterial and Osteogenic Performance in Preventing Osteomyelitis Recurrence. [PDF]
ACS OmegaChukaew S +5 more
europepmc +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Advanced Healthcare Materials, EarlyView.Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian +7 more
wiley +1 more source
, 2019 Scaffolding as a metaphor in teaching and learning describes the adaptive and temporary support provided by a more competent person (e.g., teacher or adult) to a less competent person (e.g., student or child). Scaffolding, with its link to Vygotskian sociocultural theory, has been popularized and applied to a number of education realms.
openaire +1 more source
MotifLeadDB: A Hierarchical Structural Data Set for Congeneric Ligand Binding Activity Change. [PDF]
J Chem Inf ModelKim N, Bae B, Jung N, Seok C, Park H.
europepmc +1 more source
Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
Advanced Healthcare Materials, EarlyView.ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
A Leakage-Aware Drug Discovery Workflow for PKM2 and MAPK1 Integrating Scaffold Validation, Molecular Docking and Structural Triage. [PDF]
Int J Mol SciUcar F, Kati N.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Application of Patient-Specific PCL/<i>β</i>TCP Scaffolds for Reconstruction of Maxillomandibular Bone Defects: A Case Series. [PDF]
Case Rep DentFarajpour H +4 more
europepmc +1 more source