Results 261 to 270 of about 954,074 (407)

Apoptotic Cleavage of Scaffold Attachment Factor A (SAF-A) by Caspase-3 Occurs at a Noncanonical Cleavage Site [PDF]

open access: hybrid, 2000
Michael Kipp   +4 more
openalex   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Modified pegRNAs mitigate scaffold-derived prime editing by-products. [PDF]

open access: yesNat Commun
Antoniou P   +14 more
europepmc   +1 more source

Comparative study of seeding methods for three-dimensional polymeric scaffolds [PDF]

open access: bronze, 2000
Karen J. L. Burg   +9 more
openalex   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

open access: yesAdvanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim   +8 more
wiley   +1 more source

Transcriptomic Profile of Human Osteoblast-like Cells Grown on Trabecular Titanium. [PDF]

open access: yesInt J Mol Sci
Castoldi G   +11 more
europepmc   +1 more source

REGENERATIVE SIGNALS FOR INTESTINAL EPITHELIAL ORGANOID UNITS TRANSPLANTED ON BIODEGRADABLE POLYMER SCAFFOLDS FOR TISSUE ENGINEERING OF SMALL INTESTINE1,2

open access: bronze, 1999
Stephen S. Kim   +7 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

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