Results 261 to 270 of about 160,812 (310)
Some of the next articles are maybe not open access.
Annals of Internal Medicine, 2017
The editorialists discuss the findings of Zhang and colleagues' systematic review in light of one company's recent announcement that it is halting sales of BVSs.
Sanket S, Dhruva, Jeptha P, Curtis
openaire +2 more sources
The editorialists discuss the findings of Zhang and colleagues' systematic review in light of one company's recent announcement that it is halting sales of BVSs.
Sanket S, Dhruva, Jeptha P, Curtis
openaire +2 more sources
Proceedings of the 19th ACM Conference on Computer-Supported Cooperative Work & Social Computing, 2016
The development of strong social and emotional skills is central to personal wellbeing. Increasingly, these skills are being taught in schools through well researched curricula. Such social-emotional learning (SEL) curricula are most effective if reinforced by parents, thus transferring the skills into everyday contexts.
Petr Slovák +7 more
openaire +1 more source
The development of strong social and emotional skills is central to personal wellbeing. Increasingly, these skills are being taught in schools through well researched curricula. Such social-emotional learning (SEL) curricula are most effective if reinforced by parents, thus transferring the skills into everyday contexts.
Petr Slovák +7 more
openaire +1 more source
Journal of Knee Surgery, 2014
There are two scaffold products designed for meniscal reconstruction or substitution of partial meniscal defects that are currently available in the Europe: the collagen meniscal implant (CMI; Ivy Sports Medicine, Gräfelfing, Germany) and the polymer scaffold (PS; Actifit, Orteq Bioengineering, London, United Kingdom). The CMI has demonstrated improved
Kevin R, Myers +2 more
openaire +2 more sources
There are two scaffold products designed for meniscal reconstruction or substitution of partial meniscal defects that are currently available in the Europe: the collagen meniscal implant (CMI; Ivy Sports Medicine, Gräfelfing, Germany) and the polymer scaffold (PS; Actifit, Orteq Bioengineering, London, United Kingdom). The CMI has demonstrated improved
Kevin R, Myers +2 more
openaire +2 more sources
Intuitive Ordering of Scaffolds and Scaffold Similarity Searching Using Scaffold Keys
Journal of Chemical Information and Modeling, 2014Scaffold Keys-scaffold descriptors based on simple topological parameters such as number of ring and chain atoms, number and type of heteroatoms, and other simple structural features-are presented. Scaffold Keys enable intuitive ordering of scaffolds from small and simple to large and complex, ordering that is consistent with the way medicinal chemists
openaire +2 more sources
Drug Discovery Today: Technologies, 2004
The aim of scaffold hopping is to discover structurally novel compounds starting from known active compounds by modifying the central core structure of the molecule. Scaffold hopping is a central task of modern medicinal chemistry requiring a multitude of techniques, which are discussed in this article.
Hans-Joachim, Böhm +2 more
openaire +2 more sources
The aim of scaffold hopping is to discover structurally novel compounds starting from known active compounds by modifying the central core structure of the molecule. Scaffold hopping is a central task of modern medicinal chemistry requiring a multitude of techniques, which are discussed in this article.
Hans-Joachim, Böhm +2 more
openaire +2 more sources
Journal of Learning Disabilities, 1998
To situate the concept of scaffolding within a broader context than that addressed by Stone, I discuss it with respect to (a) the historical context of learning disabilities, (b) the emerging focus on learners activity, (c) the reification of learning disabilities, and (d) the unintended effects that frequently occur as a by-product of injudicious (and
openaire +2 more sources
To situate the concept of scaffolding within a broader context than that addressed by Stone, I discuss it with respect to (a) the historical context of learning disabilities, (b) the emerging focus on learners activity, (c) the reification of learning disabilities, and (d) the unintended effects that frequently occur as a by-product of injudicious (and
openaire +2 more sources
The Restriction Scaffold Problem
Journal of Computational Biology, 2002Most shotgun sequencing projects undergo a long and costly phase of finishing, in which a partial assembly forms several contigs whose order, orientation, and relative distance is unknown. We propose here a new technique that supplements the shotgun assembly data by experimentally simple and commonly used complete restriction digests of the target.
Amir Ben-Dor +3 more
openaire +2 more sources
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000
The concept of scaffolds that can be equipped with artificial biochemically active sites has gained recent interest in the field of protein design. Members of the lipocalin protein family represent promising model systems in this respect. Especially prototypic lipocalins, such as the retinol-binding protein or the bilin-binding protein (BBP), exhibit a
openaire +2 more sources
The concept of scaffolds that can be equipped with artificial biochemically active sites has gained recent interest in the field of protein design. Members of the lipocalin protein family represent promising model systems in this respect. Especially prototypic lipocalins, such as the retinol-binding protein or the bilin-binding protein (BBP), exhibit a
openaire +2 more sources