Results 111 to 120 of about 288,835 (288)

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Biomaterial Scaffolds for Periodontal Tissue Engineering

Journal of Functional Biomaterials
Advanced periodontitis poses a significant threat to oral health, causing extensive damage and loss of both hard and soft periodontal tissues. While traditional therapies such as scaling and root planing can effectively halt the disease’s progression ...
Huanhuan Chen, Guangying Song, Tianmin Xu, Chenda Meng, Yunfan Zhang, Tianyi Xin, Tingting Yu, Yifan Lin, Bing Han   +8 more
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Morphology and Mechanical Properties of PLLA and PCL Scaffolds

, 2013
Esperanza Dı́az, Igor Puerto, Iban Sandonis, Itsaso Ibáñez Fernández   +3 more
openalex   +2 more sources

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Human Acellular Amniotic Membrane as Skin Substitute and Biological Scaffold: A Review of Its Preparation, Preclinical Research, and Clinical Application [PDF]

, 2023
Yanqi Li, Siyu An, Chengliang Deng, Shune Xiao   +3 more
openalex   +1 more source

Exploiting the Functionality of Cerium Oxide‐Modified Carbon Nanohorns Catalysts Toward Enhanced CO2 Reduction Performance

Advanced Functional Materials, EarlyView.
A cerium oxide‐carbon nanohybrid catalyst is synthesized via two distinct routes and is integrated into H‐type cells and gas diffusion layers (GDLs) to enhance electrochemical performance. Structural variations significantly affect performance, with the solvothermal sample exhibiting higher current densities.
Alessia Pollice, Michele Cacioppo, Miriam Marchi, Miriam Moro, Francesco Paolucci, Marcella Bonchio, Maurizio Prato, Giovanni Valenti, Michele Melchionna, Paolo Fornasiero   +9 more
wiley   +1 more source

Synthesis of tercyclic scaffolds as alpha helix mimetics

, 2017
Zelong Lim
openalex   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Aryl Urea Based Scaffolds for Multitarget Drug Discovery in Anticancer Immunotherapies [PDF]

, 2021
Celia Martín-Beltrán, Raquel Gil-Edo, Germán Hernández-Ribelles, Raül Agut, Pilar Marí-Mezquita, Miguel Cardá, Eva Falomir   +6 more
openalex   +1 more source