Results 141 to 150 of about 279,058 (314)
IEEE AccessIn cloud computing and distributed databases, ensuring strong consistency and system reliability of the leader depends on distributed consensus algorithms such as Raft and Paxos.
Kiran Kumar Kondru, Saranya Rajiakodi
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Scalability and robustness of a market-based network resource allocation system
, 2005 In this paper, we consider issues related to scalability and robustness in designing a market-based multi-agent system that allocates bandwidth in a communications network.
Jennings, N. R. +2 more
core
Highly scalable OTDM router using computer controlled time slot tuner with picosecond resolution
, 1999 An optical time division multiplexing (OTDM) router, using a highly scalable time slot tuner, is discussed. Channel access in OTDM networks is achieved by using time slot tuners and all-optical demultiplexers. Timing precision of
Glesk, Ivan +8 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Scalability Analysis of the UDCOPA Protocol in Large and Massive IoT Environments [PDF]
Clustering has a very positive impact on any optimization problem on the Internet of Things (IoT) or Wireless Sensor Networks (WSN). Energy efficiency based on clustering has proved its efficiency in this area of research, increasing the lifetime of the ...
Mir, F., Meziane, F.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source