Results 131 to 140 of about 1,583,946 (364)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Scalability and Robustness of a Network Resource Allocation System Using Market-Based Agents

, 2005
In this paper, we consider issues associated with scalability and robustness in designing a market-based multi-agent system that allocates bandwidth in a communications network.
Jennings, N. R., Haque, N, Moreau, L, Jennings, NR   +3 more
core  

The feasibility, scalability and outcomes of cardiorespiratory fitness testing in primary school children

, 2016
PURPOSE: The physical activity (PA) levels and fitness of schoolchildren is increasingly a public health issue. Cardiorespiratory fitness (CRF) is a validated marker of PA levels, however there is little systematic measurement of this variable in school ...
Beedie, C., Domone, S., Wade, M., Mann, S.   +3 more
core   +1 more source

GEOBIA at the Terapixel Scale: Toward Efficient Mapping of Small Woody Features from Heterogeneous VHR Scenes

ISPRS International Journal of Geo-Information, 2019
Land cover mapping has benefited a lot from the introduction of the Geographic Object-Based Image Analysis (GEOBIA) paradigm, that allowed to move from a pixelwise analysis to a processing of elements with richer semantic content, namely objects or ...
François Merciol, Loïc Faucqueur, Bharath Bhushan Damodaran, Pierre-Yves Rémy, Baudouin Desclée, Fabrice Dazin, Sébastien Lefèvre, Antoine Masse, Christophe Sannier   +8 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

RaftOptima: An Optimised Raft With Enhanced Fault Tolerance, and Increased Scalability With Low Latency

IEEE Access
In cloud computing and distributed databases, ensuring strong consistency and system reliability of the leader depends on distributed consensus algorithms such as Raft and Paxos.
Kiran Kumar Kondru, Saranya Rajiakodi
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Scalability and robustness of a market-based network resource allocation system

, 2005
In this paper, we consider issues related to scalability and robustness in designing a market-based multi-agent system that allocates bandwidth in a communications network.
Jennings, N. R., Haque, Nadim, Moreau, Luc   +2 more
core  

Highly scalable OTDM router using computer controlled time slot tuner with picosecond resolution

, 1999
An optical time division multiplexing (OTDM) router, using a highly scalable time slot tuner, is discussed. Channel access in OTDM networks is achieved by using time slot tuners and all-optical demultiplexers. Timing precision of
Glesk, Ivan, Deng, K.-L., Glesk, I., Runser, Robert J., Prucnal, P.R., Runser, R. J., Deng, K. L., Toliver, P., Prucnal, P. R.   +8 more
core   +1 more source

LIKERT: An APPLESOFT program for the construction, administration, and scoring of Likert scales [PDF]

, 1983
Perry Morrison
openalex   +1 more source