Results 1 to 10 of about 111,192 (47)

Kropina metrics with isotropic scalar curvature [PDF]

open access: yesarXiv, 2023
In this paper, we study Kropina metrics with isotropic scalar curvature. First, we obtain the expressions of Ricci curvature tensor and scalar curvature. Then, we characterize the Kropina metrics with isotropic scalar curvature on by tensor analysis.
arxiv  

Curvature-Dimension Condition Meets Gromov's $n$-Volumic Scalar Curvature [PDF]

open access: yesSIGMA 17 (2021), 013, 20 pages, 2020
We study the properties of the $n$-volumic scalar curvature in this note. Lott-Sturm-Villani's curvature-dimension condition ${\rm CD}(\kappa,n)$ was showed to imply Gromov's $n$-volumic scalar curvature $\geq n\kappa$ under an additional $n$-dimensional condition and we show the stability of $n$-volumic scalar curvature $\geq \kappa$ with respect to ...
arxiv   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Geometric realizations of Kaehler and of para-Kaehler curvature models [PDF]

open access: yes, 2009
We show that every Kaehler algebraic curvature tensor is geometrically realizable by a Kaehler manifold of constant scalar curvature. We also show that every para-Kaehler algebraic curvature tensor is geometrically realizable by a para-Kaehler manifold of constant scalar ...
arxiv   +1 more source

Metrics of constant negative scalar-Weyl curvature [PDF]

open access: yesarXiv, 2021
Extending Aubin's construction of metrics with constant negative scalar curvature, we prove that every $n$-dimensional closed manifold admits a Riemannian metric with constant negative scalar-Weyl curvature, that is $R+t|W|, t\in\mathbb{R}$. In particular, there are no topological obstructions for metrics with $\varepsilon$-pinched Weyl curvature and ...
arxiv  

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

On isotropic Berwald scalar curvature [PDF]

open access: yesarXiv, 2022
In this short paper, we establish a closer relation between the Berwald scalar curvature and the $S$-curvature. In fact, we prove that a Finsler metric has isotropic Berwald scalar curvature if and only if it has weakly isotropic $S$-curvature. For Finsler metrics of scalar flag curvature and of weakly isotropic $S$-curvature, they have almost ...
arxiv  

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