Results 111 to 120 of about 45,707 (265)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Unified Dark Matter Scalar Field Models
Advances in Astronomy, 2010 We analyze and review cosmological models in which the dynamics of a single scalar field accounts for a unified description of the Dark Matter and Dark Energy sectors, dubbed Unified Dark Matter (UDM) models.
Daniele Bertacca +2 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Computational visualization of scalar fields
, 2015 Scalar fields play a fundamental role in many scientific disciplines and applications. The increasing computational power offers scientists and digital artists novel opportunities for complex simulations, measurements, and models that generate large amounts of data.
openaire +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
The random free field scalar theory
Journal of High Energy PhysicsQuantum field theories with quenched disorder are so hard to study that even exactly solvable free theories present puzzling aspects. We consider a free scalar field ϕ in d dimensions coupled to a random source h with quenched disorder.
Alessandro Piazza +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Constrained instantons in scalar field theories
Journal of High Energy PhysicsInstantons, localised saddle points of the action, play an important role in describing non-perturbative aspects of quantum field theories, for example vacuum decay or violation of conservation laws associated with anomalous symmetries.
Benjamin Elder +2 more
doaj +1 more source
UniverseThe entire classical cosmological history between two extreme de Sitter vacuum solutions is discussed based on Einstein’s equations and non-equilibrium thermodynamics. The initial non-singular de Sitter state is characterised by a very high energy scale,
Pedro Eleuterio Mendonça Almeida +2 more
doaj +1 more source