Results 111 to 120 of about 1,001,350 (314)

Power, discourse and city trajectories [PDF]

open access: yes, 2001
Examines social theory and contemporary human geography in the context of urban development. Covers theoretical debates in political ecology, the cultural turn in the economy, social relations and scale, space and place, and colonialism and post ...
Boyle, Mark, Rogerson, Robert J.
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Scale Space Calibrates Present and Subsequent Spatial Learning in Barnes Maze in Mice. [PDF]

open access: yeseNeuro, 2023
Tachiki Y   +9 more
europepmc   +1 more source

Scale space analysis by stabilized inverse diffusion equations [PDF]

open access: yes, 1996
Caption title.Includes bibliographical references (p. 11).Supported by AFSOR. F49620-95-1-0083 Supported by ONR. N00014-91-J-1004 Supported in part by Boston University under the AFOSR Multidisciplinary Research Program on Reduced Signature Target ...

core  

Subspace Least Squares Multidimensional Scaling

open access: yes, 2017
Multidimensional Scaling (MDS) is one of the most popular methods for dimensionality reduction and visualization of high dimensional data. Apart from these tasks, it also found applications in the field of geometry processing for the analysis and ...
Boyarski, Amit   +2 more
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy