Results 31 to 40 of about 9,619,631 (286)

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

Assessment of the impact of a personalised nutrition intervention in impaired glucose regulation over 26 weeks: a randomised controlled trial

open access: yesScientific Reports
Dietary interventions can reduce progression to type 2 diabetes mellitus (T2DM) in people with non-diabetic hyperglycaemia. In this study we aimed to determine the impact of a DNA-personalised nutrition intervention in people with non-diabetic ...
Maria Karvela   +17 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Feature-Centered First Order Structure Tensor Scale-Space in 2D and 3D

open access: yesIEEE Access
The structure tensor method is often used for 2D and 3D analysis of imaged structures, but its results are in many cases very dependent on the user’s choice of method parameters.
Pawel Tomasz Pieta   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Ambient Noise‐Derived SmS Splitting: A New Approach to Constraining Crustal Radial Anisotropy

open access: yesGeophysical Research Letters
Recent studies have shown that crustal body wave phases, such as PmP or SmS, can be effectively retrieved from ambient noise cross‐correlations. However, few studies have used these phases to constrain crustal structures.
Jinyun Xie   +4 more
doaj   +1 more source

Ocean‐Scale Interactions From Space

open access: yesEarth and Space Science, 2019
Satellite observations of the last two decades have led to a major breakthrough emphasizing the existence of a strongly energetic mesoscale turbulent eddy field in all the oceans.
Patrice Klein   +8 more
doaj   +1 more source

Scale Development for Environmental Perception of Public Space

open access: yesFrontiers in Psychology, 2020
We developed a psychometric scale for measuring the subjective environmental perception of public spaces. In the scale development process, we started with an initial pool of 85 items identified from the literature that were related to environmental ...
Robbie Ho, Wing Tung Au
doaj   +1 more source

Free-space-coupled wavelength-scale disk resonators

open access: yesNanophotonics, 2022
Optical microresonators with low quality factor (Q$Q$) can be efficiently excited by and scatter freely propagating optical waves, but those with high Q$Q$ typically cannot.
Mirzapourbeinekalaye Babak   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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