Results 91 to 100 of about 366,438 (285)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

U-MoEMamba: A Hybrid Expert Segmentation Model for Cabbage Heads in Complex UAV Low-Altitude Remote Sensing Scenarios

Agriculture
To address the challenges of missed and incorrect segmentation in cabbage head detection under complex field conditions using UAV-based low-altitude remote sensing, this study proposes U-MoEMamba, an innovative dynamic state-space framework with a ...
Rui Li, Xue Ding, Shuangyun Peng, Fapeng Cai   +3 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

SLGMA-UNet: Comprehensive Feature Aggregation With Context-Sensitive Attention for Medical Image Segmentation

IEEE Access
Medical image segmentation is essential for clinical diagnosis and treatment planning. Existing segmentation methods encounter challenges such as managing size variations, interpreting contextual relationships, and integrating multi-source data.
Xinghuo Ye, Na Wang
doaj   +1 more source

Robust brain segmentation using histogram scale-space analysis and mathematical morphology [PDF]

, 1998
In this paper, we propose a robust fully non-supervised method dedicated to the segmentation of the brain in T1-weighted MR images. The first step consists in the analysis of the scale-space of the histogram first and second derivative. We show first that the crossings in scale-space of trajectories of extrema of different derivative orders follow ...
J. -F. Mangin, O. Coulon, V. Frouin
openaire   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Back to geometry: Efficient indoor space segmentation from point clouds by 2D–3D geometry constrains

International Journal of Applied Earth Observations and Geoinformation
This paper addresses the challenge of indoor space segmentation from 3D point clouds, which is essential for understanding interior layouts, reconstructing 3D structures, and developing indoor navigation maps.
Shengjun Tang, Junjie Huang, Benhe Cai, Han Du, Baoding Zhou, Zhigang Zhao, You Li, Weixi Wang, Renzhong Guo   +8 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

TriM-SOD: A Multi-Modal, Multi-Task, and Multi-Scale Spacecraft Optical Dataset

Space: Science & Technology
The acquisition and application of spacecraft optical data is an important part of space-based situational awareness (SSA). Spacecraft optical data processing techniques can assist in tasks such as on-orbit operation, space debris removal, and deep space
Tianyu Zhu, Hesong Li, Ying Fu
doaj   +1 more source