Results 71 to 80 of about 572,802 (294)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

PointSSM: State space model for large-scale LiDAR point cloud semantic segmentation

International Journal of Applied Earth Observations and Geoinformation
LiDAR point cloud semantic segmentation is the foundation of numerous practical applications. Recently, the Mamba, as a promising alternative to Transformer, has been getting intense attention in this field.
Dilong Li, Jianlong Guan, Ziyi Chen, Jingchen Liao, Jixiang Du   +4 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Multi-scale Feature Fusion and Transformer Network for urban green space segmentation from high-resolution remote sensing images

International Journal of Applied Earth Observation and Geoinformation, 2023
Yong Cheng, Wei Wang, Zhoupeng Ren, Yingfen Zhao, Yilan Liao, Yong Ge, Jun Wang, Jiaxin He, Yakang Gu, Yixuan Wang, Wenjie Zhang, Ce Zhang   +11 more
semanticscholar   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A scale space approach for automatically segmenting words from historical handwritten documents

IEEE Transactions on Pattern Analysis and Machine Intelligence, 2005
Many libraries, museums, and other organizations contain large collections of handwritten historical documents, for example, the papers of early presidents like George Washington at the Library of Congress. The first step in providing recognition/ retrieval tools is to automatically segment handwritten pages into words.
Manmatha, R., Rothfeder, Jamie L.
openaire   +3 more sources

ClassWise-SAM-Adapter: Parameter-Efficient Fine-Tuning Adapts Segment Anything to SAR Domain for Semantic Segmentation

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In the realm of artificial intelligence, the emergence of foundation models, backed by high computing capabilities and extensive data, has been revolutionary.
Xinyang Pu, He Jia, Linghao Zheng, Feng Wang, Feng Xu   +4 more
semanticscholar   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

DPMB-Net: Dual-Level Perturbation and Multi-Scale Boundary Attention for Semi-Supervised Temporomandibular Joint Segmentation

IEEE Access
Accurate segmentation of the temporomandibular joint (TMJ) disc and condyle from magnetic resonance imaging (MRI) is critical for clinical diagnosis and treatment planning of orofacial disorders.
Xiaoshan Pan, Bin Yao, Jing Guo, Yuzhao Liu, Gongyan Li   +4 more
doaj   +1 more source